Virology Principles and Applications 2nd Edition by John Carter, Venetia Saunders ISBN 1118629760 9781118629765

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ISBN 10: 1118629760 
ISBN 13: 9781118629765
Author: John Carter, Venetia Saunders

The second edition of Virology is an accessible introduction designed to enable students to understand the principles of virus structure, replication and genetics. The aim of this book is to help the reader appreciate the relevance of virology in the modern world, including the fields of vaccines, anti-viral drugs and cancer. There is also a chapter on prions. The second edition has been extensively revised and updated to reflect the many developments in virology and offers deeper insights into the subject. Newly-discovered viruses are discussed and there is an additional chapter on the influenza virus.

Virology Principles and Applications 2nd Table of contents:

Introduction to Virology

• 1.1 Definition and Scope of Virology
• 1.2 History of Virology
• 1.3 Basic Concepts in Virology
• 1.4 Classification of Viruses
• 1.5 The Role of Viruses in Disease and Evolution

2. Structure of Viruses

• 2.1 Basic Components of Viruses
• 2.2 Viral Morphology and Symmetry
• 2.3 Viral Genomes: DNA vs. RNA
• 2.4 Virus Families and Their Structural Characteristics
• 2.5 Methods of Studying Virus Structure

3. Virus Replication and Life Cycle

• 3.1 Viral Attachment and Entry
• 3.2 Uncoating and Genome Release
• 3.3 Transcription, Translation, and Replication
• 3.4 Viral Assembly and Maturation
• 3.5 Release of Virions and Transmission

4. Virus-Host Interactions

• 4.1 Host Range and Tropism
• 4.2 Mechanisms of Viral Entry into Host Cells
• 4.3 Immune Evasion by Viruses
• 4.4 Host Immune Responses to Viral Infections
• 4.5 Pathogenesis: Viral Damage to Host Cells

5. Viral Genetics and Evolution

• 5.1 Mutation and Genetic Variability in Viruses
• 5.2 Quasispecies and Genetic Drift
• 5.3 Recombination and Reassortment
• 5.4 Evolutionary Pressures on Viruses
• 5.5 Coevolution of Viruses and Hosts

6. Virological Techniques

• 6.1 Cultivation of Viruses in Cell Culture
• 6.2 Virus Detection: PCR, ELISA, and Microscopy
• 6.3 Virus Titration and Quantification
• 6.4 Animal Models for Viral Research
• 6.5 Genomic and Proteomic Approaches in Virology

7. Virus Transmission and Epidemiology

• 7.1 Modes of Virus Transmission (Airborne, Vector-borne, etc.)
• 7.2 Epidemiological Studies in Virology
• 7.3 Virus Reservoirs and Zoonotic Infections
• 7.4 The Role of Mutation in Pandemic Outbreaks
• 7.5 Tracking Viral Spread: Case Studies (e.g., HIV, Influenza)

8. Human Viruses and Disease

• 8.1 Respiratory Viruses (Influenza, Coronavirus, etc.)
• 8.2 Enteric Viruses and Gastrointestinal Infections
• 8.3 Hepatitis Viruses: Pathogenesis and Treatment
• 8.4 Neurotropic Viruses: Rabies, Polio, and More
• 8.5 Oncoviruses: Cancer and Viral Etiology

9. Antiviral Therapy and Vaccines

• 9.1 Antiviral Drug Development and Mechanisms of Action
• 9.2 Challenges in Antiviral Resistance
• 9.3 The Role of Vaccines in Viral Disease Prevention
• 9.4 Vaccine Development and Technology (e.g., mRNA vaccines)
• 9.5 Immunization Strategies: Global Impact and Challenges

10. Emerging Viruses and Global Health

• 10.1 The Rise of Emerging Viruses: Zika, Ebola, SARS-CoV-2
• 10.2 Virus Evolution in the Context of Globalization
• 10.3 Public Health Responses to Viral Outbreaks
• 10.4 One Health: The Intersection of Human, Animal, and Environmental Health
• 10.5 Predicting Future Viral Threats

11. Industrial and Environmental Applications of Virology

• 11.1 Viruses in Biotechnology (Gene Therapy, Vectors)
• 11.2 Phage Therapy and Bacteriophage Applications
• 11.3 Virus-based Bioinsecticides and Agricultural Applications
• 11.4 The Role of Viruses in Environmental Processes
• 11.5 Viral Diagnostics and Molecular Tools in Industry

12. Ethical, Legal, and Social Implications of Virology

• 12.1 Ethical Considerations in Virus Research
• 12.2 Public Perception of Viruses and Vaccine Hesitancy
• 12.3 Bioterrorism and Dual-Use Research
• 12.4 Legal Issues in Virus Patent and Ownership
• 12.5 The Future of Global Collaboration in Virology

13. Conclusion and Future Directions

• 13.1 The Future of Virology as a Science
• 13.2 New Frontiers: Synthetic Virology and Artificial Life
• 13.3 Anticipating the Next Viral Pandemic
• 13.4 Interdisciplinary Approaches in Virology
• 13.5 Final Thoughts and Reflections

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