Dietary AGEs and Their Role in Health and Disease 1st Edition Jaime Uribarri 1351646354 9781351646352

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Product details:

• ISBN 10: 1351646354
• ISBN 13: 9781351646352
• Author: Jaime Uribarri 

Of the many dietary factors associated with inflammation and oxidative stress, a specific group are food-derived pro-inflammatory and pro-oxidant compounds, so-called advanced glycation end products (AGEs). While AGEs have been recognized as factors in the pathogenesis of diabetic complications, the importance of AGEs of dietary origin as a factor in human disease is of more recent concern. This book presents data from the past two decades on the role of AGEs in causing chronic disease. It starts by defining the compounds passing through all the clinical diseases that have been associated with them and finishes by offering different therapeutic options to deal with the problem.

Table of contents:

Section I What Are AGEs?

1. What Are AGEs, Their Chemical Structure, and How Can They Be Measured?

2. How AGEs Cause Disease: Cellular Mechanisms

3. AGE Clearance Mechanisms

4. How Are AGEs Handled by the Kidney?

Section II The Modern Diet & AGEs: How Do Exogenous AGEs Become Incorporated into Our Body?

5. Dietary Advanced Glycation End Products: Animal Studies

6. AGEs in Infant Formulas: Chemical and Physiological Aspects

7. Potentially Toxic Food Components Formed by Excessive Heat Processing

8. Is Part of the Fructose Effects on Health Related to Increased AGE Formation?

Section III Role of AGEs in the Pathogenesis of Chronic Diseases

9. Role of Advanced Glycation Products in Health and Disease in Children

10. The Role of Advanced Glycation End Products in Cognitive Decline and Dementia

11. Advanced Glycation End Products and Polycystic Ovarian Syndrome

12. Dietary AGEs and Diabetic Complications

13. Dietary AGEs and Aging

14. AGE and Erectile Dysfunction: Any Role of Dietary AGEs?

15. Biological Implications of Diet-Derived Advanced Glycation End Products on Carcinogenesis

16. Advanced Glycation End Products and Their Receptors in Aspiration-Induced Acute Respiratory Distress Syndrome

17. Dietary AGEs in the Development and Progression of Chronic Kidney Disease

18. Dietary AGEs May Have Different Effects in People with Vegetarian versus Omnivorous Eating Patterns

19. Effects of Dietary AGEs in the Gut Microbiota Composition

20. Associations of Circulating AGE Levels and Cardiovascular Disease-Incidence and Outcome

21. Pathological Role of AGEs in Osteoporosis

22. Is There a Relationship between Dietary AGEs and Food Allergies?

23. Quantitation and Potential Health Effects of Advanced Glycation End Products in Pet Foods

24. The Role of AGEs in the Pathogenesis of Macrovascular Complications in Diabetes Mellitus

Section IV Therapeutic Alternatives to Deal with Dietary AGEs

25. Plant-Derived Products with Antiglycation Activity

26. Dietary Intake of AGEs and ALEs and Inflammation: Nutritional Aspects

27. Effects of a Low-AGE Diet on Insulin Sensitivity

28. Clinical Trials with an AGE-Restricted Diet

29. Blocking Gastrointestinal Absorption of AGEs

30. Antagonizing the Effects of Dietary Advanced Glycation End Products on Endothelial Dysfunction

31. Methylglyoxal and Other AGEs: Good and Bad Dual Role in the Body

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