Zika in Focus Postnatal Clinical Laboratorial and Radiological Aspects 1st Edition Maria De Fátima Viana Vasco Aragão 3319536435 9783319536439

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Product details:

• ISBN 10: 3319536435
• ISBN 13: 9783319536439
• Author: Maria De Fátima, Viana Vasco Aragão 

This book addresses the most important postnatal features of Zika virus infection, providing important information on its epidemiology, pathology, clinical aspects, imaging and laboratory diagnosis. Since the report of a Zika virus infection epidemic in Northeastern Brazil in 2015, the world has paid close attention to this emergent disease. Historically, this has been the third outbreak of Zika infection described (preceded by outbreaks in Micronesia and French Polynesia), but for the first time the association with congenital microcephaly and other neurological co-morbidities in infants from women infected with the Zika virus was observed. Since then, government bodies, public health agencies, medical societies and scholars have joined forces to understand this disease, and to promote its prevention and management. Currently, the relationship between Zika virus and microcephaly is well established, as well as the most characteristic findings of congenital Zika syndrome (e.g. microcephaly, arthrogryposis, ophthalmologic and hearing abnormalities).

Table of contents:

Zika Virus: History and Infectology

Introduction

Historical Evolution

Sexual Transmission

Breastfeeding

Transfusion

Clinical Spectrum

Classic Form

Neurological Manifestations

Microcephaly

Congenital Zika

Clinical Aspects

Laboratory Diagnosis

Diagnosis by Neuroimaging

Current Situation in Pernambuco: IMIP

Treatment

Zika and Breastfeeding

Accompaniment

References

Congenital Zika Syndrome: Clinical Aspects

References

Ocular Findings in Children with Congenital Zika Syndrome

Introduction

The History Behind the Discovery

Pregnancy History and Prevalence of Ocular Findings

The Ocular Findings

Pathophysiology of Ocular Lesions

Risk Factors Associated with Ocular Findings

Ocular Findings in the Absence of Microcephaly

The Centers of Diseases Control (CDC) Recommendations

Ocular Findings in Adults During Acute Infection

Conclusion

References

Zika Virus: Laboratory Diagnosis

References

Neuroimaging Findings of Congenital Zika Syndrome

Prenatal Findings

Postnatal Findings

Brain Calcifications

Malformations of Cortical Development

Brain Hypoplasia and Ventriculomegaly

Corpus Callosum Abnormalities

Brainstem and Cerebellum Abnormalities

Enlarged Cisterna Magna and Extra-Axial Subarachnoid Space

Delayed Myelination

Vascular Abnormalities

Reduced Thickness of Spinal Cord and Ventral Roots

References

Radiological Differential Diagnosis of Microcephaly

Cytomegalovirus (CMV)

Toxoplasmosis

Syphilis

Rubella

Herpes Simplex Virus (HSV)

Varicella Zoster Virus (VZV)

Human Immunodeficiency Virus (HIV)

References

Cases: Spectrum of Computed Tomography in Congenital Zika Syndrome

Cases: Spectrum of Magnetic Resonance Imaging in Congenital Zika Syndrome

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