Miller’s Anesthesia 9th Edition by Michael Gropper, Lars Eriksson, Lee Fleisher, Jeanine Wiener Kronish, Neal Cohen, Kate Leslie ISBN 0323811078 9780323811071

Miller’s Anesthesia 9th Edition by Michael Gropper, Lars I. Eriksson, Lee A. Fleisher, Jeanine P. Wiener Kronish, Neal H. Cohen, Kate Leslie – Ebook PDF Instant Download/Delivery: 0323811078, 978-0323811071
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ISBN 10:    0323811078
ISBN 13: 978-0323811071
Author:       Michael Gropper, Lars I. Eriksson, Lee A. Fleisher, Jeanine P. Wiener Kronish, Neal H. Cohen, Kate Leslie

Miller’s Anesthesia 9th Table of contents:

VOLUME 1

Section I. Introduction

1. The Scope of Modern Anesthetic Practice

   • Introduction
   • Forces That Will Change Practice (Fig. 1.1)
   • Conclusions

2. Anesthesia and Analgesia in the Global Context

   • Introduction
   • Section 1: Anesthesia and “Global Health”
   • Section 2: Evolution of Anesthesia Care Models and Challenges Around the World
   • Section 3: Essentials for Practice in Resource-Constrained Settings
   • Appendix 1: Links and Useful Resources
   • Conclusions

3. Perioperative Medicine

   • Introduction
   • Perioperative Management
   • Models of Perioperative Care
   • Conclusion

4. Informatics in Perioperative Medicine

   • Introduction
   • Computer Systems
   • Computer Networks
   • The Internet
   • Information Security
   • Standards for Healthcare Data Exchange
   • Regulation of Electronic Data Exchange
   • The Nature of Healthcare Information in the Anesthesia Encounter
   • Development and Deployment of Anesthesia Information Management Systems
   • Integration of Anesthesia Care Information with Operating Room Information Systems
   • Development of Decision Support Tools
   • Integration with the Enterprise Electronic Health Record
   • Billing System Interactions
   • Challenges in Anesthesia Information Management System Implementation
   • Additional Uses for Collected Data
   • Interactions of Electronic Devices with the Delivery of Anesthesia Care
   • Conclusion

5. Quality Improvement in Anesthesia Practice and Patient Safety

   • What Is Quality?
   • Approaches to Quality Assessment
   • Quality Improvement Measures and Tools
   • Sources of Quality Improvement Information
   • Examples of Quality Improvement Programs
   • The Future: Research, Education, and Ethics
   • Summary

6. Avoiding Patient Harm in Anesthesia: Human Performance and Patient Safety

   • What this Chapter is About: An Overview
   • Human Performance and Patient Safety in Anesthesia: Why is this Important?
   • Nature of the Anesthesia Professional’s Operational Domain: A Dynamic and Complex Environment
   • Nature of the Anesthesia Professional’s Work: Task Variation and Workload Management
   • Patient Safety on the Individual and Team Level
   • Patient Safety on the Organizational Level
   • The Bigger Picture: Patient Safety Efforts on the U.S. National and International Level
   • Conclusion and Outlook
   • Appendix 6.1: Online Links and Valuable Public Sources

7. Patient Simulation

   • What This Chapter Is About: An Overview
   • Simulation in Anesthesia: Why Is It Important?
   • Application of Simulation in Anesthesia and Healthcare
   • History, Development, and Types of Simulators and Simulation
   • Simulation Fidelity and Classification of Simulators
   • Sites of Simulation
   • Simulation Team Training Participants: Who Should Be Trained and in What Composition?
   • Patient Simulation Timing: Announced in Advance Versus Unannounced in Advance
   • Scopes of Simulation in Healthcare: The 12 Dimensions of Simulation
   • Crisis Resource Management (ACRM; CRM): Part of Modern Patient Simulation Team Training
   • Anatomy of a Patient Simulation Team Training Exercise
   • Scenario Design and Execution: Knowing the Learning Objectives and Making It Real
   • Debriefing: Heart and Soul of Patient Simulation
   • Qualification and Certification of Simulation Instructors
   • Accreditation of Simulation Programs, Sites, and Centers
   • Benefits, Effectiveness, and Ecological Validity of Simulation Training
   • Cost of Patient Simulation and Simulation Centers
   • Using Simulation for Assessment of Clinical Performance
   • Simulation Societies and Simulation Journals
   • The Future of Patient Simulation in Anesthesia
   • Appendix 7.1: Online Links and Useful Resources

8. Ethical Aspects of Anesthesia Care

   • Ethical Theory
   • Clinical Ethics
   • Special Issues in Informed Consent and Informed Refusal
   • Ethics of Anesthesia Involving Pregnant Women
   • The Uncooperative Patient—Coercion and Restraint
   • Truth-Telling—Disclosure of Errors and Apology
   • Research Ethics

Section II. Anesthetic Physiology

9. Consciousness, Memory, and Anesthesia

   • Introduction
   • Consciousness
   • Memory
   • Organization and Function of Normal Memory
   • Effects of Anesthetic Drugs on Declarative Memory Function in Humans
   • Nonhuman Studies of Anesthetic Effects on Memory Processes and Behavior in the Medial Temporal Lobe
   • Human and Nonhuman Studies of Anesthetic Effects on Fear Memory Systems
   • Anesthetic Effects on Implicit Memory Function

10. Sleep Medicine

• Definition of Sleep
• Physiology
• How to Assess Sleep
• Sleep and Breathing
• Sleep and Anesthesia: Two Unequal Twins Influencing Perioperative Medicine
• Sleep and Sedation in the Intensive Care Unit
• Acknowledgment

11. Cerebral Physiology and the Effects of Anesthetic Drugs

• The Anatomy of the Cerebral Circulation
• Effects of Anesthetics on Cerebral Blood Flow and Cerebral Metabolic Rate
• Other Effects of Anesthetics on Cerebral Physiology
• Cerebral Physiology in Pathologic States

12. Neuromuscular Physiology and Pharmacology

• Neuromuscular Transmission
• Neuromuscular Junction
• Drug Effects on Postjunctional Receptors
• Biology of Prejunctional and Postjunctional Nicotinic Acetylcholine Receptors
• Neuromuscular Junction at Extremes of Age

13. Respiratory Physiology and Pathophysiology

• Respiratory Physiology is Central to the Practice of Anesthesia
• Pulmonary Physiology in Health
• Ventilation
• Static Lung Volumes—Functional Residual Capacity
• Respiratory Mechanics
• Distribution of Inspired Gas
• Perfusion
• Clinical Assessment of Lung Function
• Intraoperative Respiratory Events
• Ventilation-Perfusion Matching During Anesthesia
• Factors that Influence Respiratory Function During Anesthesia
• Lung Function After Cardiac Surgery
• Protective Ventilation
• Postoperative Physiotherapy
• Intraoperative Hyperoxia
• Effect of Sleep on Respiration

14. Cardiac Physiology

• Physiology of the Intact Heart
• Cellular Cardiac Physiology
• Control of Cardiac Function

15. Gastrointestinal Physiology and Pathophysiology

• Introduction
• Gastrointestinal Anatomy and Function
• Transit Time in Health and Disease
• Methods of Evaluating Colonic Motility
• The Effects of General Anesthesia on Bowel Function
• Effect of Opioids on Bowel Function
• Effect of Open Abdominal Surgery, Ischemia, Stomas, and Bowel Anastomosis on Gastrointestinal Physiology and Function
• Gastrointestinal System Nociception

16. Hepatic Physiology, Pathophysiology, and Anesthetic Considerations

• Anatomy of the Liver
• Hepatic Physiology
• Evaluation of the Liver
• Hepatic Pathophysiology
• Strategies for Minimizing Blood Loss

17. Renal Anatomy, Physiology, Pharmacology, and Evaluation of Function

• Introduction
• Organization of the Kidney
• Induced Hypotension

18. Basic Principles of Pharmacology

• Introduction
• Pharmacokinetic Models
• Special Interests in Anesthetic Pharmacokinetics
• Pharmacodynamic Principles
• Special Populations
• Summary

19. Inhaled Anesthetics: Mechanisms of Action

• History
• Integrated Effects on Central Nervous System Function
• Identification of Molecular Sites of Anesthetic Action
• Cellular Mechanisms
• Simple Circuits and Complex Networks
• Research Strategies for the Future
• Summary

20. Inhaled Anesthetic Uptake, Distribution, Metabolism, and Toxicity

• Introduction
• Uptake and Distribution of Inhaled Anesthetics
• Synthesis of the Model and Inhaled Anesthetic Induction: PK/PD
• Metabolism and Toxicity of Inhaled Anesthetics

21. Pulmonary Pharmacology and Inhaled Anesthetics

• Introduction
• Inhaled Anesthetics
• Mucociliary Function and Surfactant
• Nonvolatile Inhaled Agents
• Summary

22. Inhaled Anesthetics: Delivery Systems

• Standards and Guidelines for Anesthesia Workstations
• Functional Anatomy of the Anesthesia Workstation
• Checking Your Anesthesia Workstation

23. Intravenous Anesthetics

• Propofol
• Barbiturates
• Benzodiazepines
• Flumazenil
• Phencyclidines (Ketamine)
• Etomidate
• Dexmedetomidine
• Droperidol
• Summary

24. Opioids

• Introduction
• Pharmacology of Opioids
• Neurophysiologic Effects of Opioids
• Respiratory and Cardiovascular Effects of Opioids
• Endocrinologic Effects of Opioids
• Renal and Urodynamic Effects of Opioids
• Effects of Opioids on Digestive Organs
• Other Opioid Effects
• Pharmacokinetics and Pharmacodynamics of Opioids
• Anesthetic Techniques Using Opioids
• Drug Interactions with Opioids

25. Nonopioid Pain Medications

• Introduction
• Nonsteroidal Anti-inflammatory Drugs
• Acetaminophen
• Calcium Channel Blockers
• Sodium Channel Blockers

26. Intravenous Drug Delivery Systems

• Introduction
• Pharmacokinetic Considerations
• Pharmacodynamic Considerations
• Designing Dosing Regimens
• Intravenous Infusion Devices and Technologies
• Future Perspectives

27. Pharmacology of Neuromuscular Blocking Drugs

• History and Clinical Use
• Principles of Action at the Neuromuscular Junction
• Pharmacology of Succinylcholine and Nondepolarizing Neuromuscular Blockers
• Special Populations

28. Reversal (Antagonism) of Neuromuscular Blockade

• History and Current Management Practices
• Drugs Used to Reverse Neuromuscular Blockade

29. Local Anesthetics

• Basic Pharmacology
• Mechanism of Action
• Clinical Pharmacology
• Toxicity
• Prolonged-Duration and Sensory-Selective Local Anesthetics
• Mechanisms of Failure and Genetic Variants
• Conclusions

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