A New Kind of Computational Biology Cellular Automata Based Models for Genomics and Proteomics Parimal Pal Chaudhuri 9811316392 9789811316395

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Product details:

• ISBN 10: 9811316392 
• ISBN 13: 9789811316395
• Author: Pal Chaudhuri

This book reflects more than three decades of research on Cellular Automata (CA), and nearly a decade of work on the application of CA to model biological strings, which forms the foundation of ‘A New Kind of Computational Biology’ pioneered by the start-up, CARLBio. After a brief introduction on Cellular Automata (CA) theory and functional biology, it reports on the modeling of basic biological strings with CA, starting with the basic nucleotides leading to codon and anti-codon CA models. It derives a more involved CA model of DNA, RNA, the entire translation process for amino acid formation and the evolution of protein to its unique structure and function. In subsequent chapters the interaction of Proteins with other bio-molecules is also modeled. The only prior knowledge assumed necessary is an undergraduate knowledge of computer programming and biology. The book adopts a hands-on, “do-it-yourself” approach to enable readers to apply the method provided to derive the CArules and comprehend how these are related to the physical ‘rules’ observed in biology. In a single framework, the authors have presented two branches of science – Computation and Biology.

Table of contents:

1. Computational Biology—First Principle Informatics Modelling

2. Design of Cellular Automata Rules for Biomolecules

3. Cellular Automata Model for Ribonucleic Acid (RNA)

4. Cellular Automata Model for Deoxyribonucleic Acid (DNA)

5. Cellular Automata (CA) Model for Protein

6. Current and Next Phases of Development of cLife (CA-Based Life)

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