Acute Brain Impairment Scientific Discoveries and Translational Research Philip 1788013379 9781788013376

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Product details:

• ISBN 10: 1788013379
• ISBN 13: 9781788013376
• Author: Philip V Peplow

A rise in the number of young and old patients suffering from a stroke or traumatic brain injury has led to the need for better drug development and treatment, as well as diagnosis and prevention of ischemic stroke and traumatic brain injury. This book provides a comprehensive overview of scientific advancements in these areas.

Chapters provide the latest knowledge in neuroscience, biotechnology, and personalized medicine applicable to acute brain injuries. Development of neuroprotective drugs is treated in detail. Chemical biomarkers for detection, imaging and preventative strategies are covered to provide medicinal chemists with a broad view of translational aspects of the field.

Table of contents:

Chapter 1 Transient Ischemic Attack, Traumatic Brain Injury, and Ischemic

Chapter 2 Inflammatory Changes in Cerebral Ischemic Injury: Cel

Chapter 3 Biomarkers of Acute Brain Injury and Surrogate Endpoints in Traumatic Brain Injure

Chapter 4 Difficulties of Translating Outcomes from Animal Studies to Cl

Chapter 5 Neuroprotective Therapies for Ischemic Stroke

Chapter 6 The Molecular Neuroprotective Strategies in Cerebral Isch

Chapter 7 Identification of MicroRNAs as Targets for Treatment of Ischemic Str

Chapter 8 Combined Drug–Diagnostic Test Co-development for Predicting and Preventing Br

Chapter 9 Advances in Diagnostics and Treatment of Neurotoxicity after S

Chapter 10 Functional Predictors for Prognosis and Recovery after Mild Traumatic Brain Injury

Chapter 11 Predictors for Prognosis and Recovery from Unconsciousness

Chapter 12 Neurotoxicity in Spinal Cord Impairments

Chapter 13 Advanced Approaches in Stem Cell Therapy for Stroke an

Chapter 14 Testing and Mechanisms of Neuroprotective Agents for Cere

Chapter 15 Difficulties in Clinical Trials to Treat Traumatic Brain Injury and Str

Chapter 16 Challenges in Using Biomarkers in Central Nervous System Applicat

Chapter 17 Resolving Difficult Case Scenarios by Incorporating Stroke Biomarkers in C

Chapter 18 Development of Novel Test Platforms for the Assessment of Brain I

Chapter 19 Advancements and Challenges in Hyperacute Stroke Translational Research

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