Advances in Structure and Activity Relationship of Coumarin Derivatives 1st Edition by Penta,Santhosh 9780128037973 0128037970
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ISBN 10:0128037970
ISBN 13:9780128037973
Author:Penta,Santhosh
Advances in Structure and Activity Relationship of Coumarin Derivatives covers the structural behavior of various coumarin derivatives for various potential pharmaceutical applications. Based on substitution targeted for active sites, the book takes a rational approach for designing new and specific potent drugs, optimizing existing ones, and developing novel reactions. This focused primer describes the chemical structure and activity of coumarin derivatives to explore the effects of different substituents at specific positions, and their properties for effective bioactivity.
- Accessible and current coverage of coumarin derivatives from structure to potential applications
- Application of SAR technology to predict bioactivity of the derivatives based on its chemical structure
- Information for researchers in medicinal chemistry, pharmaceutical sciences, and related fields
Advances in Structure and Activity Relationship of Coumarin Derivatives 1st Table of contents:
Chapter 1. Introduction to Coumarin and SAR
1.1 What is Coumarin?
1.2 Types of Coumarin and Examples
1.3 What is SAR?
1.4 Why SAR?
1.5 Application of SAR
1.6 When SAR Studies are Done
1.7 Needs of SAR
1.8 SAR of Coumarin in Disease Biology
1.9 Summary
Chapter 2. Antimicrobial Agents
2.1 Introduction
2.2 What is an Antibacterial Agent?
2.3 Antiviral Agents
2.4 Antifungal Agents
Chapter 3. Antitumor Agents
3.1 Introduction
3.2 Unsubstituted Coumarin
3.3 Substitution in Coumarin Nucleus
Chapter 4. Neuroprotective Agents
4.1 Introduction
4.2 Anti-Alzheimer Agents
Chapter 5. Antidepressing Agents
5.1 Introduction
Chapter 6. Anti-Inflammatory Agents
6.1 Introduction
Chapter 7. Antioxidant Agents
7.1 Introduction
7.2 Coumarin Nucleus
7.3 SAR by Bond Dissociation Enthalpy
7.4 Radical Scavenging Activity
7.5 Antioxidant Capacity (or Total Antioxidant Capacity)
7.6 Chelating Activity
Chapter 8. Anticoagulant Agents
8.1 Introduction
Chapter 9. Miscellaneous Agents
9.1 Dopamine Inhibatory Activity
9.2 DNA-PK Inhibitory Activity
9.3 Antipsychotic Agents
9.4 Tyrosinase Inhibitors
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