Anaerobiosis and stemness : an evolutionary paradigm for therapeutic applications 1st Edition Ivanović 0128006110 9780128005408 9780128006115

This completed downloadable of Anaerobiosis and stemness : an evolutionary paradigm for therapeutic applications 1st Edition Ivanović

Instant downloaded Anaerobiosis and stemness : an evolutionary paradigm for therapeutic applications 1st Edition Ivanović pdf docx epub after payment.

Product details:

• ISBN 10: 0128006110 
• ISBN 13: 9780128005408, 9780128006115
• Author: Ivanović

Anaerobiosis and Stemness: An evolutionary paradigm provides a context for understanding the many complexities and evolutionary features of stem cells and the clinical implications of anaerobiosis stem cells.  Combining theoretical and experimental knowledge, the authors provide a broad understanding of how the absence or low concentration of oxygen can play an influential role in the maintenance and self-renewal of stem cells and stem cell differentiation.  This understanding has clinical implications for the fields of regenerative medicine, cancer biology and transplantation, as well as cell engineering and cell therapy. Anaerobiosis and Stemness is an important resource for stem cell and developmental biologists alike, as well as oncologists, cancer biologists, and researchers using stem cells for regeneration.

Table of contents:

1. What Entity Could Be Called a Stem Cell?
2. In Situ Normoxia versus “Hypoxia”
Part One. Anaerobiosis and Stem Cell Entity
3. The “Hypoxic” Stem Cell Niche
4. Low O2 Concentrations and the Maintenance of Stem Cells Ex Vivo
5. Quiescence/Proliferation Issue and Stem Cell Niche
6. Metabolic Peculiarities of the Stem Cell Entity: Energetic Metabolism and Oxidative Status
7. Molecular Basis of “Hypoxic” Signaling, Quiescence, Self-Renewal, and Differentiation in Stem Cells
Part Two. Anaerobic-to-Aerobic Eukaryote Evolution: A Paradigm for Stem Cell Self-Renewal, Commitment and Differentiation?
8. Evolution of Eukaryotes with Respect to Atmosphere Oxygen Appearance and Rise: Anaerobiosis, Facultative Aerobiosis, and Aerobiosis1
9. Evolution of Mitochondria in Eukaryotes versus Mitochondria “Maturing” from the Stage of Stem Cells to Committed Progenitors and Mature Cells1
10. Evolutionary Origins of Stemness: Relationship between Self-Renewal and Ancestral Eukaryote Biology; Conservation of Self-Renewal Principle
11. Metabolic and Genetic Features of Ancestral Eukaryotes versus Metabolism and “Master Pluripotency Genes” of Stem Cells
12. Other Features Concerning the Analogy “Stem Cells: Primitive Eukaryotes”: ABC Transporters’ Anaerobiosis/Stemness Link
14. Cancer Stem Cell Case and Evolutionary Paradigm

People also search:

anaerobic staphylococcus

anaerobic steps

an anaerobic environment

do anaerobic cells still exist

scientists study anaerobic fermentation in yeast cells