Autophagy and Signaling 1st Edition Esther Wong 1351646974 9781351646970

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Product details:

• ISBN 10: 1351646974
• ISBN 13: 9781351646970
• Author: Esther Wong

Autophagy and Signaling is an up-to-date overview of the many signaling pathways regulating autophagy in response to different cellular needs. Discussion includes the status and future directions of autophagy signaling research with respect to different aspects of health and disease. These include the roles of autophagy in regulating cell fate, immune response and host defense, nutrient sensing and metabolism, neural functions and homeostasis. The mechanisms and significance of cross-talk between autophagy and other cellular processes is also explored. Lastly, alterations in autophagy observed in aging and age-related pathologies are described.

Table of contents:

Section I: Signaling Pathways Regulating Autophagy

Chapter 1 Regulation of Autophagy by AMPK

Chapter 2 Signal Regulation of WIPI Protein Function in Macroautophagy

Section II: Autophagy and Cell Fate

Chapter 3 Cross Talk between Autophagy and Cell Death Pathways: Toward Understanding a System

Chapter 4 Autophagy, Cellular Senescence, and Cancer

Section III: Autophagy in Immunity and Metabolism

Chapter 5 Autophagy and Regulation of Immune Response

Chapter 6 Cilia-Related Autophagy in Nutrient Sensing

Chapter 7 Regulation of Lipophagy

Section IV: Autophagy in Neural Homeostasis and Neurodegeneration

Chapter 8 Mitophagy and Neurodegeneration

Chapter 9 Aggrephagy

Chapter 10 Chaperone-Mediated Autophagy and Neurodegeneration

Chapter 11 Autophagy in Synaptic Structure and Function

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