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ISBN 10: 3030114602
ISBN 13: 978-3030114602
Author: Héctor M. Alvarez
Rhodococcus are metabolically versatile actinobacteria frequently found in the environment with potential applications in bioremediation, biotransformations and biocatalysis, among other biotechnological processes. These microorganisms are currently the subject of research in many countries of the world. The number of publications and patents on rhodococci has intensified significantly within the last years. In this context, the knowledge acquired during the last decade about basic aspects of Rhodococcus biology is significant and promising about their future prospects. Several genomic projects of Rhodococcus members are now available and in progress through public and private efforts due to the increasing interest in their use for biotechnology. The large Rhodococcus genomes containing a multiplicity of catabolic genes, a high genetic redundancy of biosynthetic pathways and a sophisticated regulatory network reflect the complexity of Rhodococcus biology. The combination of functional genomics studies with biochemical and physiological knowledge is providing new insights, which will enable the biotechnological use of rhodococci.
This Microbiology Monographs volume provides a thorough review of many aspects of biochemistry, physiology and genetics of Rhodococcus, in the context of new genomic information. Expert international scientists contributed with reviews on the extraordinary capability of Rhodococcusgenus for biodegradation of diverse compounds and bioremediation, biosynthesis of lipids and biosurfactants, adaptation and tolerance to solvents, interaction with metals and biotechnological applications. Chapters dealing with taxonomy, genomes and plasmids, and oligotrophic and central metabolism are also included in this volume. Moreover, the book includes basic aspects of the phytopathogenic R. fascians.
Biology of rhodococcus 2nd Table of contents:
1. Refined Systematics of the Genus Rhodococcus Based on Whole Genome Analyses
- Overview of genomic tools and their role in classifying Rhodococcus species
- Evolutionary relationships and taxonomic insights derived from whole genome sequences
2. Genomics of Rhodococcus
- Genome sequencing and annotation of Rhodococcus species
- Genetic diversity and insights into the metabolic and functional capabilities of Rhodococcus
3. Central Metabolism of Species of the Genus Rhodococcus
- Key metabolic pathways and biochemical processes in Rhodococcus
- Role of central metabolism in ecological adaptability and biodegradation
4. Oligotrophic Growth of Rhodococcus
- Mechanisms enabling Rhodococcus to thrive in nutrient-limited environments
- Physiological and genetic adaptations for survival in oligotrophic conditions
5. Adaptation of Rhodococcus to Organic Solvents
- Genetic and biochemical strategies employed by Rhodococcus to tolerate and degrade organic solvents
- Impact of solvent exposure on cell physiology and survival mechanisms
6. Degradation of Alkanes in Rhodococcus
- Genetic pathways and enzymes involved in alkane degradation
- Biochemical pathways for the breakdown of hydrocarbons by Rhodococcus species
7. Biodegradation of Nitriles by Rhodococcus
- Role of Rhodococcus in the bioremediation of nitrile compounds
- Enzymes and metabolic pathways involved in nitrile degradation
8. The Desulfurization Pathway in Rhodococcus
- Mechanisms of sulfur metabolism and desulfurization in Rhodococcus
- Industrial applications of desulfurization pathways, particularly in petroleum and biofuels
9. Bioremediation of Contaminated Environments Using Rhodococcus
- Utilization of Rhodococcus for environmental cleanup and waste management
- Case studies on the application of Rhodococcus in bioremediation of soil, water, and air pollution
10. Production of Trehalolipid Biosurfactants by Rhodococcus
- Biosynthesis pathways of trehalolipids in Rhodococcus
- Applications of trehalolipid biosurfactants in industrial and environmental contexts
11. Biology of Triacylglycerol Accumulation by Rhodococcus
- Mechanisms of triacylglycerol (TAG) synthesis and storage in Rhodococcus
- Potential applications in biofuel production and lipid-based biotechnologies
12. Interaction of Rhodococcus with Metals and Biotechnological Applications
- Metal tolerance and uptake mechanisms in Rhodococcus
- Biotechnological applications of Rhodococcus in metal bioremediation and metal recovery
13. Plant-Associated Rhodococcus Species: For Better and for Worse
- Beneficial and harmful interactions between Rhodococcus and plants
- Roles of Rhodococcus in plant growth promotion, pathogenicity, and stress responses
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