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Bone Morphogenetic Proteins Systems Biology Regulators 1st Edition by Slobodan Vukicevic, Kuber T Sampath ISBN 9783319475059 978-3319475059

Name: Bone Morphogenetic Proteins Systems Biology Regulators 1st Edition by Slobodan Vukicevic, Kuber T Sampath ISBN 9783319475059 978-3319475059
SKU: EB-5760308
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Bone Morphogenetic Proteins Systems Biology Regulators 1st Edition Slobodan Vukicevic Digital Instant Download

Author(s): Slobodan Vukicevic, Kuber T. Sampath

ISBN(s): 9783319475059, 3319475053

Edition: 1

File Details: PDF, 10.50 MB

Year: 2017

Language: English

SKU: EB-5760308 Category: Medicine Tags: Kuber T. Sampath, Slobodan Vukicevic

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Bone Morphogenetic Proteins Systems Biology Regulators 1st Edition by Slobodan Vukicevic, Kuber T. Sampath – Ebook PDF Instant Download/Delivery: 9783319475059, 978-3319475059

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Product details:

ISBN 10: 9783319475059

ISBN 13: 978-3319475059

Author: Slobodan Vukicevic, Kuber T. Sampath

This book focuses on the salient features of the biology of Bone Morphogenetic Proteins and the advances in our understanding of their structure and function and of downstream signaling, as well as their governance in systems biology from bone and dentin to kidney, cancer, diabetes, iron homeostasis and angiogenesis, including rare musculoskeletal disorders. BMPs, also referred to as growth and differentiation factors, are members of the TGF-beta superfamily and are highly conserved from fruit flies to mammals and are responsible for the formation of practically every organ during embryo development and involved in adult tissue injury and repair. BMPs establish their extracellular gradient by interacting with their respective antagonists and regulate their function through SMAD-dependent down-stream signaling effector genes.

This volume is aimed at scientists and professionals dealing with metabolic disorders, nutrition, systems biology diseases, rare musculoskeletal conditions, and disorders related to iron metabolism, including anemia of chronic disease, hereditary hemochromatosis and beta thalassemia.

Historical Perspective of Bone Morphogenetic Proteins
The Systems Biology of Bone Morphogenetic Proteins
Embryonic Skeletogenesis and Craniofacial Development
BMP and BMP Regulation: Structure and Function
Novel In Vitro Assay Models to Study Osteogenesis and Chondrogenesis for Human Skeletal Disorders
Toward Advanced Therapy Medicinal Products (ATMPs) Combining Bone Morphogenetic Proteins (BMP) and Cells for Bone Regeneration
BMP Signaling in Articular Cartilage Repair and Regeneration: Potential Therapeutic Opportunity for Osteoarthritis
BMPs in Orthopaedic Medicine: Promises and Challenges
Osteogrow: A Novel Bone Graft Substitute for Orthopedic Reconstruction
Biology of Spine Fusion and Application of Osteobiologics in Spine Surgery
BMPs in Dental Medicine: Promises and Challenges
Bone Morphogenetic Protein-7 and Its Role in Acute Kidney Injury and Chronic Kidney Failure
Bone Morphogenetic Protein Signaling in Pulmonary Arterial Hypertension
BMP Signaling in Fibrodysplasia Ossificans Progressiva, a Rare Genetic Disorder of Heterotopic Ossification
The Central Role of BMP Signaling in Regulating Iron Homeostasis
BMPs in Inflammation
Physiological and Pathological Consequences of Vascular BMP Signaling
Bone Morphogenetic Proteins in the Initiation and Progression of Breast Cancer

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