Cancer-Leading Proteases: Structures, Functions, and Inhibition 1st Edition Dr. Satya Prakash Gupta 9780128181690

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Product details:

• ISBN 13: 9780128181690
• Author: Dr. Satya Prakash

Cancer-Leading Proteases: Structures, Functions, and Inhibition presents a detailed discussion on the role of proteases as drug targets and how they have been utilized to develop anticancer drugs. Proteases possess outstanding diversity in their functions. Because of their unique properties, proteases are a major focus of attention for the pharmaceutical industry as potential drug targets or as diagnostic and prognostic biomarkers. This book covers the structure and functions of proteases and the chemical and biological rationale of drug design relating to how these proteases can be exploited to find useful chemotherapeutics to fight cancers.

Table of contents:

1
Cancer-leading proteases: An introduction

2
Potential roles of protease inhibitors in anticancer therapy

3
Studies on cysteine proteases and their inhibitors for anticancer drug

4
Ubiquitin-specific proteases as targets for anticancer drug therapies

5
Aspartic proteases: Potential drug targets for anticancer drug

6
Inhibitors of HIV protease in cancer therapy

7
Serine proteases in ovarian cancer

8
Serine proteases leading to prostate cancer: Structures, functions, and development of anticancer drugs

9
HCV NS3 serine protease as a drug target for the development of drugs against hepatocellular carcinoma (liver cancer)

12
Rhomboid proteases leading to cancer: Structures, functions, and

References
13
KRAS: Structure, function, and development of anticancer drugs

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