Computational Methods in Synthetic Biology 2nd Edition by Mario Andrea Marchisio ISBN 1071608215 9781071608210

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Product details:

ISBN 10: 1071608215

ISBN 13: 9781071608210 

Author: Mario Andrea Marchisio

This second edition book provides complete coverage of the computational approaches currently used in Synthetic Biology.  New chapters detail computational methods and algorithms for the design of bio-components, insight on CAD programs, analysis techniques, and distributed systems. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, application details for both the expert and non-expert reader, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, Computational Methods in Synthetic Biology, Second Edition aims to feature a broad overview of the research areas that can be met in the area of in silico Synthetic Biology.

Table of contents:

1. Using A Design Of Experiments Approach To Inform The Design Of Hybrid Synthetic Yeast Promoters

2. Computational Design Of Multiplex Oligonucleotide-Based Assays

3. Computational Methods For The Design Of Recombinase Logic Circuits

4. Modular Modeling Of Genetic Circuits In SBML Level 3

5. CRISPR-ERA: A Webserver For Guide RNA Design Of Gene Editing And Regulation

6. IGUIDE Method For CRISPR Off-Target Detection

7. Web-Based Base Editing Toolkits: BE-Designer And BE-Analyzer

8. Synthetic Gene Circuit Analysis And Optimization

9. Monitoring Single S. Cerevisiae Cells With Multifrequency Electrical Impedance Spectroscopy In An Electrode-Integrated Microfluidic Device

10. Construction Of Protein Expression Network

11. Systems-Theoretic Approaches To Design Biological Networks With Desired Functionalities

12. A Deterministic Compartmental Modeling Framework For Disease Transmission

13. Computer Aided Assembly And Verification Of Synthetic Chromosomes

14. Minimal Genome Design Algorithms Using Whole-Cell Models

15. Tn-Core: Functionally Interpreting Transposon-Sequencing Data With Metabolic Network Analysis

16. Genome-Scale Metabolic Modeling Of Escherichia Coli And Its Chassis Design For Synthetic Biology Applications

17. A Systems Bioinformatics Approach To Interconnect Biological Pathways

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Tags: Mario Andrea Marchisio, Computational Methods, in Synthetic Biology