Contemporary Practice in Clinical Chemistry 4th Edition by William Clarke, Mark Marzinke ISBN 0128158336 9780128158333

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ISBN 10:      0128158336
ISBN 13: 978- 0128158333
Author:    William Clarke, Mark Marzinke 

Contemporary Practice in Clinical Chemistry, Fourth Edition, provides a clear and concise overview of important topics in the field. This new edition is useful for students, residents and fellows in clinical chemistry and pathology, presenting an introduction and overview of the field to assist readers as they in review and prepare for board certification examinations. For new medical technologists, the book provides context for understanding the clinical utility of tests that they perform or use in other areas in the clinical laboratory. For experienced laboratorians, this revision continues to provide an opportunity for exposure to more recent trends and developments in clinical chemistry.

• Includes enhanced illustration and new and revised color figures
• Provides improved self-assessment questions and end-of-chapter assessment questions

Contemporary Practice in Clinical Chemistry 4th Table of contents:

• Introduction

  • Overview of Clinical Chemistry and Its Role in Healthcare
  • The Evolution of Clinical Chemistry Practices
  • Goals and Structure of the Book

• Chapter 1: Fundamentals of Clinical Chemistry

  • Introduction to Laboratory Medicine
  • Basic Biochemistry for Clinical Chemists
  • Key Laboratory Techniques and Methodologies
  • Quality Control and Assurance in Clinical Chemistry

• Chapter 2: Analytical Techniques in Clinical Chemistry

  • Spectrophotometry and Colorimetry
  • Chromatography Methods (HPLC, GC)
  • Mass Spectrometry in Clinical Chemistry
  • Electrophoresis and Immunoassays

• Chapter 3: Laboratory Instrumentation and Automation

  • Principles of Laboratory Instrumentation
  • Advances in Automation and High-Throughput Screening
  • Maintenance and Calibration of Clinical Instruments
  • Troubleshooting Instrumental Issues

• Chapter 4: Biochemical Markers in Disease Diagnosis

  • Enzymes and Their Clinical Significance
  • Biomarkers for Cardiovascular Diseases
  • Tumor Markers and Their Role in Oncology
  • Hormones and Endocrine Disorders

• Chapter 5: Acid-Base Balance and Electrolytes

  • Physiology of Acid-Base Homeostasis
  • Clinical Assessment of Acid-Base Disorders
  • Electrolyte Imbalance and Its Clinical Consequences
  • Laboratory Diagnosis and Management of Electrolyte Disorders

• Chapter 6: Protein Chemistry and Clinical Applications

  • Protein Structure and Function in Health and Disease
  • Diagnostic Testing for Protein Disorders
  • The Role of Proteins in Kidney, Liver, and Cardiovascular Diseases
  • Electrophoresis and Protein Profiling in Disease Diagnosis

• Chapter 7: Lipid Metabolism and Clinical Chemistry

  • Lipid Metabolism and Its Regulation
  • Lipid Disorders: Hyperlipidemia, Dyslipidemia, and Their Clinical Impact
  • Laboratory Testing for Lipid Disorders
  • Advances in Lipid Management and Therapeutic Monitoring

• Chapter 8: Carbohydrates and Glycobiology

  • Carbohydrate Metabolism and Disorders
  • Diabetes Mellitus: Diagnosis and Monitoring
  • Glycobiology in Clinical Chemistry
  • Clinical Testing for Glycemic Control

• Chapter 9: Clinical Chemistry in Infectious Disease

  • Laboratory Diagnosis of Infectious Agents
  • Serological Testing and PCR Applications
  • Emerging Pathogens and Diagnostic Challenges
  • Antimicrobial Resistance and Its Implications in Clinical Chemistry

• Chapter 10: Toxicology and Drug Monitoring

  • Principles of Clinical Toxicology
  • Toxicology Screening and Detection Methods
  • Therapeutic Drug Monitoring (TDM)
  • Drugs of Abuse and Legal Implications

• Chapter 11: Molecular Diagnostics in Clinical Chemistry

  • The Role of Molecular Biology in Clinical Chemistry
  • PCR, Next-Generation Sequencing, and Other Molecular Tools
  • Genetic Testing and Personalized Medicine
  • Ethical and Legal Considerations in Molecular Diagnostics

• Chapter 12: Advances in Clinical Chemistry and Future Trends

  • Emerging Technologies in Clinical Chemistry
  • The Role of Artificial Intelligence and Machine Learning in Diagnostics
  • Point-of-Care Testing and Its Impact on Clinical Chemistry
  • Future Directions in Clinical Chemistry

• Chapter 13: Laboratory Management and Ethics

  • Laboratory Organization and Workflow
  • Ethical Issues in Clinical Chemistry Practice
  • Legal and Regulatory Aspects of Clinical Laboratory Work
  • Leadership in the Clinical Chemistry Laboratory

• Conclusion

  • Summary of Key Concepts and Practices in Clinical Chemistry
  • The Future of Clinical Chemistry in Medical Practice

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