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Product details:
- ISBN 10: 0128184817
- ISBN 13: 9780128184813
- Author: Prashant Kesharwani
Drug Discovery Targeting Drug-Resistant Bacteria explores the status and possible future of developments in fighting drug-resistant bacteria. The book covers the majority of microbial diseases and the drugs targeting them. In addition, it discusses the potential targeting strategies and innovative approaches to address drug resistance. It brings together academic and industrial experts working on discovering and developing drugs targeting drug-resistant (DR) bacterial pathogens. New drugs active against drug-resistant pathogens are discussed, along with new strategies being used to discover molecules acting via new modes of action. In addition, alternative therapies such as peptides and phages are included.
Pharmaceutical scientists, microbiologists, medical professionals, pathologists, researchers in the field of drug discovery, infectious diseases and microbial drug discovery both in academia and in industrial settings will find this book helpful.
Table of contents:
Chapter 1 – Antibiotics: past, present, and future
Chapter 2 – Mechanisms of antibacterial drug resistance and approaches to overcome
Chapter 3 – Antibiotics targeting Gram-negative bacteria
Chapter 4 – Recent development of antibacterial agents to combat drug-resistant Gram-positive bacter
Chapter 5 – Repurposing nonantibiotic drugs as antibacterials
Chapter 6 – Drugs against Mycobacterium tuberculosis
Chapter 7 – Combating biothreat pathogens: ongoing efforts for countermeasure development and unique
Chapter 8 – New approaches to antibacterial drug discovery
Chapter 9 – New strategies and targets for antibacterial discovery
Chapter 10 – Importance of efflux pumps in subjugating antibiotic resistance
Chapter 11 – Phage therapy—bacteriophage and phage-derived products as anti-infective drugs
Chapter 12 – Drug discovery targeting drug-resistant nontuberculous mycobacteria
Chapter 13 – New strategies to combat drug resistance in bacteria
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