Genetics For Dummies 3rd Edition by Tara Rodden Robinson,Lisa Spock 9781119633037 1119633036

Part 1: The Lowdown on Genetics: Just the Basics

Chapter 1: Welcome to Genetics: What’s What and Who’s Who

What Is Genetics?

Genetics as a Career

Chapter 2: Basic Cell Biology

Looking Around Your Cell

Mitosis: Splitting Up

Meiosis: Making Cells for Reproduction

Chapter 3: Visualize Peas: Discovering the Laws of Inheritance

Gardening with Gregor Mendel

Speaking the Language of Inheritance

Simplifying Inheritance

Finding Unknown Alleles

Applying Basic Probability to the Likelihood of Inheritance

Solving Simple Genetics Problems

Chapter 4: Law Enforcement: Mendel’s Laws Applied to Complex Traits

Dominant Alleles Rule … Sometimes

Alleles Causing Complications

Making Life More Complicated

Uncovering More Exceptions to Mendel’s Laws

Part 2: DNA: The Genetic Material

Chapter 5: DNA: The Basis of Life

Chemical Ingredients of DNA

Examining Different Varieties of DNA

Digging into the History of DNA

Chapter 6: Chromosomes: The Big Picture

Deconstructing the Double Helix

Anatomy of a Chromosome

Two Chromosomes Are Better than One (or Three)

Sex Chromosomes: Is It a Boy or Girl?

Chapter 7: Replication: A Copy Machine for DNA

Unzipped: Creating the Pattern for More DNA

How DNA Copies Itself

Replication in Eukaryotes

How Circular DNAs Replicate

Chapter 8: DNA Sequencing: Decoding the Genome

Sequencing: Reading the Language of DNA

Sequencing Your Way to the Human Genome

Trying on a Few Genomes

Chapter 9: RNA: DNA’s Close Cousin

You Already Know a Lot about RNA

Transcription: Copying DNA’s Message into RNA’s Language

Post-transcription Processing

Chapter 10: Translating the Genetic Code

Discovering the Good in a Degenerate

Meeting the Translating Team

Taking the Translation Trip

Proteins Are Precious Polypeptides

Chapter 11: Gene Expression: What a Cute Pair of Genes

Getting Your Genes Under Control

To Be Expressed or Not To Be Expressed?

Regulating Gene Expression: A Time and Place for Everything

Controlling Transcription Before It Starts

Regulation of Gene Transcription: Flipping the Switch

Retroactive Control: Things That Happen after Transcription

Gene Control Lost in Translation

Prokaryotic Gene Expression

Part 3: Genetics and Your Health

Chapter 12: When Things Go Wrong: Changes in DNA Sequence

Heritable or Not Heritable?

Facing the Consequences of Sequence Variants

Sorting Out Terminology

What Causes Sequence Variants?

Evaluating Options for DNA Repair

Chapter 13: Chromosome Disorders: It’s All a Numbers Game

Chromosome Numbers: No More and No Less

Aneuploidy of the Autosomal Chromosomes

Aneuploidy of the Sex Chromosomes

Exploring Variations in Chromosome Structure

How Chromosomes Are Studied

Non-Invasive Prenatal Testing for Aneuploidy

Chapter 14: Taking a Closer Look at the Genetics of Cancer

Defining Cancer

Recognizing Cancer as a DNA Disease

Breaking Down the Types of Cancers

Chapter 15: Genetic Counseling, Risk Assessment, and Genetic Testing

Getting to Know Genetic Counselors

Building and Analyzing a Family Tree

Autosomal Inheritance: No Differences Among the Sexes

Found on Sex Chromosomes: Sex-linked Inheritance

Testing for Genetic Disorders

Chapter 16: Treating Genetic Disorders and Using Genetics to Tailor Treatment

Alleviating Genetic Disease through Gene Therapy

Inserting Healthy Genes into the Picture

Finding Vehicles to Get Genes to Work

Progress on the Gene Therapy Front

Utilizing Genetic Information for Precision Medicine

Part 4: Genetics and Your World

Chapter 17: Tracing Human History and the Future of the Planet

Genetic Variation Is Everywhere

Breaking Down the Hardy-Weinberg Law of Population Genetics

Mapping the Gene Pool

Changing Forms over Time: The Genetics of Evolution

Chapter 18: Solving Mysteries Using DNA

Rooting through Your DNA to Find Your Identity

Investigating the Scene: Where’s the DNA?

Employing DNA to Catch Criminals (And Free the Innocent)

It’s All Relative: Finding Family

Chapter 19: Genetic Makeovers: Using Genetic Engineering to Change the Genome

Genetically Modified Organisms Are Everywhere

Old Genes in New Places

Looking at the GMO Menagerie

Transgenic plants

Changing the Blueprint: Gene Editing

Chapter 20: Giving Ethical Considerations Their Due

Profiling Genetic Discrimination

Ordering Up Designer Babies

Ethical Issues Surrounding Genetic Testing

Informed Consent

Patient Autonomy

Privacy and Confidentiality

Incidental Findings

Direct-to-Consumer Testing

Practicing Safe Genetic Treatments

Genetic Property Rights

Part 5: The Part of Tens

Chapter 21: Ten Defining Events in Genetics

The Publication of Darwin’s “The Origin of Species”

The Rediscovery of Mendel’s Work

DNA Transformation

The Discovery of Jumping Genes

The Birth of DNA Sequencing

The Invention of PCR

The Development of Recombinant DNA Technology

The Invention of DNA Fingerprinting

The Birth of Developmental Genetics

The Work of Francis Collins and the Human Genome Project

Chapter 22: Ten Hot Issues in Genetics

Direct-to-Consumer Genetic Testing

Whole Exome Sequencing

Whole Genome Sequencing

Stem Cell Research

The ENCODE Project

Proteomics

Gene Chips

Evolution of Antibiotic Resistance

Circumventing Mother Nature

Genetics from Afar

Glossary