Glutathione In The Nervous System First Edition Shaw

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Product details:

• ISBN-10: 1560326433
• ISBN-13: 978-1560326434
• Author: Christopher Ari Shaw

Table of contents:

Part I: History, Evolution, and Localization of Glutathione in the Nervous System

1. Multiple Roles of Glutathione in the Nervous System

2. The Discovery of the GSH Receptor in Hydra and Its Evolutionary Significance

3. Carrier-Mediated GSH Transport at the Blood-Brain Barrier and Molecular Characterization of Novel Brain GSH Transporters

4. Antibodies to Glutathione: Production, Characterization, and Immunocytochemical Application to the Central Nervous System

Part II: Multiple Roles of Glutathione in Neural Function

5. Role of Astrocytes in Maintaining Cerebral Glutathione Homeostasis and in Protecting the Brain Against Xenobiotics and Oxidative Stress

6. Glutathione and the Regulation of Apoptosis in the Nervous System

7. Possible Modulation by Glutathione of Glutamatergic Neurotransmission

8. Glutathione and Glutathione Derivatives: Possible Modulators of Ionotropic Glutamate Receptors

9. Excitatory Actions of GSH on Neocortex

10. Medicinal Chemistry of Glutathione and Glutathione Analogs in the Mammalian Central Nervous System

Part III: Glutathione and Neurological Disease

11. Glutathione in Brain Aging and Neurodegenerative Disorders

12. The Glutathione Redox State and Zinc Mobilization from Metallothionein and Other Proteins with Zinc-Sulfur Coordination Sites

13. Glutathione Release and Nitrosoglutathione Presence in the CNS: Implications for Schizophrenia

14. The Role of Altered Glutathione Status in the Development of Parkinson’s Disease

15. Glutathione, Cysteine, and the Neuromelanin Pathway: Potential Roles in the Pathogenesis of Parkinson’s Disease—a New Hypothesis

16. Free-Radical Toxicity in Amyotrophic Lateral Sclerosis

17. Oxidative Stress and Neurological Diseases: Is Glutathione Depletion a Common Factor?

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