Green and sustainable medicinal chemistry : methods, tools and strategies for the 21st Century pharmaceutical industry 1st Edition by Louise Summerton, Helen F Sneddon, Leonie C Jones, James H Clark- Ebook PDF Instant Download/Delivery: 1782624678, 978-1782624677
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Product details:
ISBN 10: 1782624678
ISBN 13: 978-1782624677
Author: Louise Summerton, Helen F Sneddon, Leonie C Jones, James H Clark
Pharmaceutical manufacturing was one of the first industries to recognize the importance of green chemistry, with pioneering work including green chemistry metrics and alternative solvents and reagents. Today, other topical factors also have to be taken into consideration, such as rapidly depleting resources, high energy costs and new legislation. This book addresses current challenges in modern green chemical technologies and sustainability thinking. It encompasses a broad range of topics covered by the CHEM21 project – Europe’s largest public-private partnership project which aims to develop a toolbox of sustainable technologies for green chemical intermediate manufacture. Divided into two sections, the book first gives an overview of the key green chemistry tools, guidance and considerations aimed at developing greener processes, before moving on to look at cutting-edge synthetic methodologies. Featuring innovative research, this book is an invaluable reference for chemists across academia and industry wanting to further their knowledge and understanding of this important topic.
Table of contents:
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Foreword: An Introduction to CHEM21 Chemical Manufacturing Methods for the 21st Century Pharmaceutical Industries
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Chapter 1: Green and Sustainable Chemistry: An Introduction
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Chapter 2: Tools for Facilitating More Sustainable Medicinal Chemistry
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Chapter 3: Renewable Solvent Selection in Medicinal Chemistry
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Chapter 4: Beyond Mass-based Metrics: Evaluating the Greenness of Your Reaction
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Chapter 5: The Importance of Elemental Sustainability and Critical Element Recovery for the Pharmaceutical Industry
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Chapter 6: Presence, Fate and Risks of Pharmaceuticals in the Environment
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Chapter 7: Benign by Design
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Chapter 8: From Discovery to Manufacturing: Some Sustainability Challenges Presented by the Requirements of Medicine Development
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Chapter 9: Medicinal Chemistry: How “Green” is Our Synthetic Tool Box?
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Chapter 10: Design of Experiments (DoE) for Greener Medicinal Chemistry
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Chapter 11: Pd-catalysed Cross-couplings for the Pharmaceutical Sector and a Move to Cutting-edge C–H Bond Functionalization: Is Palladium Simply Too Precious?
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Chapter 12: The Growing Impact of Continuous Flow Methods on the Twelve Principles of Green Chemistry
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Chapter 13: Green Catalytic Direct Amide Bond Formation
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Chapter 14: Synthetic Biology for Organic Syntheses
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Chapter 15: Biocatalysis for Medicinal Chemistry
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Chapter 16: Base Metals in Catalysis: From Zero to Hero
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Chapter 17: ‘Green’ and Sustainable Halogenation Processes
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Tags: Louise Summerton, Helen F Sneddon, Leonie C Jones, James H Clark, Green, Sustainable, Medicinal Chemistry, Methods, Tools, Strategies, Pharmaceutical Industry