Hematological Malignancies 1st Edition Franklin R Moore 9781627033572

Hematological Malignancies 1st Edition Franklin R Moore – Ebook Instant Download/Delivery ISBN(s): 9781627033572

Product details:

• ISBN 13: 9781627033572
• Author: Franklin

Increased knowledge on the pathogenesis of hematologic diseases has been translated into diagnostic and prognostic applications.   Hematopathology and laboratory hematology were among the first disciplines to embrace molecular diagnostics.  Hematological Malignancies:Methods and Protocols, explores molecular-based assays frequently used in the routine diagnostic hematopathology and laboratory hematology.  Many of these protocols were initially developed as research applications and were further refined as they transitioned to the diagnostic laboratory. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

Table of contents:

Quantitative BCR-ABL1 RQ-PCR Fusion Transcript Monitoring in Chronic Myelogenous Leukemia

Detection of BCR-ABL1 Kinase Domain Mutations Causing Imatinib Resistance in Chronic Myelogenous Leukemia

Laboratory Detection of JAK2 V617F in Human Myeloproliferative Neoplasms

c-kit Mutational Analysis in Paraffin Material

Detection of Recurrent Cytogenetic Abnormalities in Acute Lymphoblastic and Myeloid Leukemias Using Fluorescence In Situ Hybridization

Liquid Bead Array Technology in the Detection of Common Translocations in Acute and Chronic Leukemias

Molecular Genetic Tests for FLT3, NPM1, and CEBPA in Acute Myeloid Leukemia

Flow Cytometric Monitoring of Residual Disease in Acute Leukemia

Chimerism Analysis Following Hematopoietic Stem Cell Transplantation

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