Malaria Immune Response to Infection and Vaccination 1st Edition by Maria M Mota, Ana Rodriguez ISBN 9783319452081 3319452088

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Product details:

ISBN 10:  3319452088

ISBN 13:  9783319452081

Author:  Maria M. Mota, Ana Rodriguez

Currently, malaria kills more than 300,000 people per year, making it a top priority of world leaders and international organizations, who are working towards implementing and coordinating efforts to eradicate this disease. An effective malaria vaccine is recognized as the key element that will decide between success and failure in this fight. At present, despite intensive research efforts, such a vaccine is not yet available for use. However, there are a number of advanced candidate vaccines with high chances of success in the short term. 

Malaria: Immune Response to Infection and Vaccination provides a comprehensive view on the immune response to malaria and to the different vaccines under development. The book offers the following:

– Contributions by top research leaders in the field,

– Comparisons of the immune responses to both malaria infection and malaria vaccines, which are traditionally treated separately,  

– Coverage of the immune responses to the different stages of malaria, which are frequently treated as separate fields of research.

Table of contents: 

1. Innate Immunity to Malaria

2. Mechanisms of Adaptive Immunity to Plasmodium Liver-Stage Infection: The Known and Unknown

3. Adaptive Immunity to Plasmodium Blood Stages

4. Pathogenetic Immune Responses in Cerebral Malaria

5. A Role for Autoimmunity in the Immune Response Against Malaria

6. Whole-Sporozoite Malaria Vaccines

7. Immune Responses to the RTS,S/AS01 Malaria Vaccine Candidate: Lessons from Human Immunology, Parasitologic and Clinical Evaluations

8. Viral Vector Vaccines for Liver-Stage Malaria

9. Epitopic Malaria Vaccines Comprised of Minimal T- and B-Cell Epitopes of the P. falciparum CS Protein

10. Immune Responses to Whole-Organism Blood-Stage Malaria Vaccines

11. Subunit Blood-Stage Malaria Vaccines

12. Antimalarial Transmission-Blocking Vaccines

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Tags: Maria M Mota, Ana Rodriguez, Malaria, Immune Response, Infection, Vaccination