Managing Health in the Genomic Era: A Guide to Family Health History and Disease Risk 1st Edition Vincent 0128160160 9780128160169

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Product details:

• ISBN-10 ‏ : ‎ 0128160160
• ISBN-13 ‏ : ‎ 9780128160169
• Author: Vincent Henrich

In Managing Health in the Genomic Era: A Guide to Family Health History and Disease Risk, Drs. Vincent C. Henrich, Lori A. Orlando, and Brian H. Shirts discuss the practical considerations surrounding the use of genomic and genetic tests to manage patient health, to provide adult disease risk assessment, to improve diagnosis, and to support effective interventions and treatment. In 10 chapters, evidence-based information and case studies are described and examine the central place of family health history (FHH) in genomic medicine, tools and strategies for compiling and analyzing family health history, how to identify existing and novel genetic markers, how to identify lineage specific (or rare) variants within families, and how to find effective interventions based on genetic testing results and FHH. Factors that influence clinical practice, including gene-environment interactions, FHH social networking, direct to consumer (DTC) genetic testing and data sharing, algorithms for analyzing genetic data, and patient counseling are discussed from the standpoint of clinical practice.

Table of contents:

Chapter 1 The growing medical relevance and value of family health history

Chapter 2 Family health history’s place in genomic medicine

Chapter 3 The connection between genetic variation, family health history, and disease risk

Chapter 4 Family-specific genetic variants: Principles, detection, and clinical interpretation

Chapter 5 Genes and cancer: Implications for FHH analysis

Chapter 6 Using family health history to identify and reduce modifiable disease risks

Chapter 7 Technology for family health history and collection and analysis

Chapter 8 Family health history and genetic counseling

Chapter 9 Current and future trends in diagnostics and treatment

Chapter 10 Current and future trends to integrate family health history with clinic

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