Neurobiology of Depression Road to Novel Therapeutics 1st Edition Joao 0128133341 9780128133347

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Product details:

• ISBN-10: 0128133341 
• ISBN-13: 9780128133347
• Author: Joao Quevedo

Neurobiology of Depression: Road to Novel Therapeutics synthesizes the basic neurobiology of major depressive disorder with discussions on the most recent advances in research, including the interacting pathways implicated in the pathophysiology of MDD, omics technologies, genetic approaches, and the development of novel optogenetic approaches that are changing research perspectives and revolutionizing research into depression. These basic foundational understandings on the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research are combined in this book to aid advanced students and researchers in their understanding of MDD.

Table of contents:

Chapter 1: The Classification of Depression: Embracing Phenotypic Heterogeneity in the Era of the RD
Chapter 2: The Role of Environmental and Psychosocial Factors in Depression
Chapter 3: Gene-Environment Interactions and Epigenetic Mechanisms in Depression
Chapter 4: Pathophysiology of Cognitive Impairment in Depression
Chapter 5: Anhedonia in Depression: Mechanisms, Assessment, and Therapeutics
Chapter 6: The Neurotrophic Hypothesis of Depression Revisited: New Insights and Therapeutic Implica
Chapter 7: The Monoamine Hypothesis of Depression Revisited: Could It Mechanistically Novel Antidepr
Chapter 8: Neuro-Immune Interactions in Depression: Mechanisms and Translational Implications
Chapter 9: The Hypothalamic-Pituitary-Adrenal Axis in Depression: Molecular Regulation, Pathophysiol
Chapter 10: Intracellular Signaling Pathways Implicated in the Pathophysiology of Depression
Chapter 11: The Long-Lasting Neurobiological Scars of Early-Life Stress: Implications for the Neurob
Chapter 12: Molecular, Cellular, and Circuit Basis of Depression Susceptibility and Resilience
Chapter 13: More Than a Gut Feeling: Emerging Roles of the Microbiome in the Pathophysiology and Tre
Chapter 14: Optogenetics: Illuminating the Neural Circuits of Depression
Chapter 15: Mitochondrial Dysfunction and Oxidative Stress: Relevance to the Pathophysiology and Tre
Chapter 16: Obesity and Depression: Shared Pathophysiology and Translational Implications
Chapter 17: Depression and Cardiovascular Risk: Epidemiology, Mechanisms, and Implications
Chapter 18: Poststroke Depression: Pathophysiology and Treatment Strategies
Chapter 19: Is Depression Associated With Accelerated Aging? Mechanisms and Implications
Chapter 20: Relationship Between Complicated Grief and Depression: Relevance, Etiological Mechanisms
Chapter 21: A Neural Circuit-Based Model for Depression Anchored in a Synthesis of Insights From Fun
Chapter 22: Could Depression be Preventable? Evidence and Perspectives
Chapter 23: Treating Depression in the Era of Precision Medicine: Challenges and Perspectives
Chapter 24: Neurobiological Aspects of Functional Recovery in Major Depressive Disorder
Chapter 25: Diet and Depression: From Epidemiology to Novel Therapeutics
Chapter 26: Physical Activity and Exercise as a Treatment of Depression: Evidence and Neurobiologica
Chapter 27: Antidepressants and Suicidality-Controversies and Possible Mechanisms
Chapter 28: Altered GABAergic Function, Cortical Microcircuitry, and Information Processing in Depre
Chapter 29: Biomarker-Based Treatment Selection: A Precision Medicine Approach for Depression
Chapter 30: Implications of Pharmacogenomics in Depression Pathophysiology and Treatment
Chapter 31: Novel Neuromodulatory Approaches for Depression: Neurobiological Mechanisms
Chapter 32: Electroconvulsive Therapy for Depression: Neurobiological Mechanisms
Chapter 33: Deep Brain Stimulation: Mechanisms Underpinning Antidepressant Effects
Chapter 34: Novel Therapeutic Targets for Major Depressive Disorder
Chapter 35: The Search for Rapid Acting Antidepressants: Research Synthesis and Perspectives
Chapter 36: Pediatric Depression
Chapter 37: Depression in Women
Chapter 38: Advances in the Neurobiology of Late-Life Depression

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