Nutraceuticals and human blood platelet function applications in cardiovascular health 1st Edition by Asim Duttaroy 1119376057 9781119376057

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ISBN-10 :  1119376057 

ISBN-13 :  9781119376057

Author: Asim K. Duttaroy 

A comprehensive review of the impact of dietary nutraceuticals on platelet function and its relationship to cardiovascular disease  Nutraceuticals and Human Blood Platelet Function offers a summary of the most current evidence on the effects of anti-platelet factors isolated mainly from food and natural sources, their structure function relationship, bioavailability, mechanisms of actions, and also information on human trials data.  The author—a noted expert in the field— explores platelet function and their roles in development of CVD, functional foods and bioactive compounds in CVD risk factors. The author highlights platelets, their mechanisms of actions, data from epidemiological studies, structure-function relationship clinical trial data, ex vivo and in vitro data. This important resource will focus primarily on human studies and emphasize functional and physiological implications of the nutritional impact on platelet function and CVD that could be an important approach to highlight the concept of preventive CVD nutrition. An authoritative text, Nutraceuticals and Human Blood Platelet Function: Offers a unique resource that connects nutrition with platelet function and its impact on cardiovascular disease Contains an evidenced-based approach, including data from human and animal clinical studies Reveals the impact of bioactive compounds and their effect on platelets Presents a text that is authored by an expert with vast experience in the field of nutrition and platelet function Written for professionals, academics, researchers, and students associated in the area of nutrition, Nutraceuticals and Human Blood Platelet Function offers a review of the most current research on the effects of platelet function and their roles in development of CVD, functional foods and bioactive compounds in CVD risk factors.

Nutraceuticals and human blood platelet function applications in cardiovascular health 1st Table of contents:

Chapter 1: Human Blood Platelets and Their Role in the Development of Cardiovascular Disease
Abbreviations Used in This Chapter
1.1 Introduction
1.2 Human Blood Platelets: Structure and Function
1.3 Platelet Activation Pathways
1.4 Platelets and Vessel Wall Interactions
1.5 Roles of Platelets in Atherosclerosis and Inflammatory Processes
1.6 Platelets and Their Role in the Development of Cardiovascular Disease
1.7 Conclusions
References
Chapter 2: Epidemiology of Cardiovascular Disease
Abbreviations Used in This Chapter
2.1 Introduction
2.2 Dietary Lipids and Cardiovascular Disease
2.3 Environmental Factors and Cardiovascular Disease
2.4 Genetic Basis of Cardiovascular Disease Incidence
2.5 Fruits and Vegetables Consumption and Cardiovascular Disease Risk Reduction
2.6 Conclusions
References
Chapter 3: n‐3 Fatty Acids and Human Platelets
Abbreviations Used in This Chapter
3.1 Introduction
3.2 Epidemiology of n‐3 Fatty Acids Intake and Cardiovascular Disease
3.3 n‐3 Fatty Acids and Platelet Function
3.4 Platelet Function and Eicosanoids
3.5 Clinical Trials with n‐3 Fatty Acids
3.6 Dietary Recommendation and Sources of n‐3 Fatty Acids
3.7 Conclusions
References
Chapter 4: Effects of Garlic, Onion, Ginger, and Turmeric on Platelet Function
Abbreviations
4.1 Introduction
4.2 Effects of Garlic (Allium Sativum) on Platelet Function
4.3 Effects of Onion (Allium Cepa L.) on Platelet Function
4.4 Effects of Ginger (Zingiber Officinale) on Platelet Function
4.5 Effects of Turmeric (Curcuma Longa) on Platelets
4.6 Conclusions
References
Chapter 5: Herbs and Platelet Function
Abbreviations Used in This Chapter
5.1 Introduction
5.2 In Vitro Platelet Aggregation Studies: Effects of Different Herb Extracts
5.3 Effects of Herbs on Signaling Molecules in Human Platelets
5.4 Conclusions
References
Chapter 6: Tomato Extract and Human Platelet Functions
Abbreviations Used in This Chapter
6.1 Introduction
6.2 Epidemiology of Tomato Consumption and Cardiovascular Disease Risk Reduction
6.3 In Vitro Studies with Water‐Soluble Tomato Extract on Human Blood Platelet Aggregation
6.4 Fruitflow®: Compositional and Structural Aspects
6.5 Human Trials
6.6 Comparing the Dietary Anti‐Platelet Fruitflow with the Anti‐Platelet Drug Aspirin
6.8 EFSA Approval of Fruitflow
6.8 Conclusions
References
Chapter 7: Dietary Nitrates and Their Anti‐Platelet Effects
Abbreviations Used in This Chapter
7.1 Introduction
7.2 Nitrate and Cardiovascular Health
7.3 Effects of Nitrates on Human Blood Platelet Function In Vitro
7.4 Clinical Studies with Dietary Nitrate: Effects on Ex Vivo Platelet Function
7.5 Conclusions
References
Chapter 8: Kiwifruit and Human Platelet Function
Abbreviations Used in This Chapter
8.1 Introduction
8.2 Kiwifruit and Its Bioactive Phytochemicals
8.3 Kiwifruits and Human Blood Platelet Function
8.4 Human Trials Using Kiwifruit and Kiwifruit Extract
8.5 Conclusions
References
Chapter 9: Polyphenols and Human Platelets
Abbreviations Used in This Chapter
9.1 Introduction
9.2 Polyphenols: Structure and Activity
9.3 Sources of Polyphenols
9.4 Dietary Intakes and Bioavailability of Polyphenols
9.5 Roles of Polyphenols in Platelet Function
9.6 Conclusions
References
Chapter 10: Effects of Ginkgo Biloba, Ginseng, Green Tea, and Dark Chocolate on Human Blood Platelet Function
Abbreviations Used in This Chapter
10.1 Introduction
10.2 Ginkgo Biloba Extract and Platelet Function
10.3 Clinical Trial with EGB761
10.4 Ginseng and Platelet Function
10.5 Green Tea (Camellia Sinensis) and its Effects on Platelet Function
10.6 Dark Chocolate and Platelet Function
10.7 Conclusions
References
Chapter 11: Plant Alkaloids and Platelet Function
Abbreviations Used in This Chapter
11.1 Introduction
11.2 Alkaloids as Anti‐Platelet Agents
11.3 Mechanism of Actions of Alkaloids
11.4 Conclusions
References
Chapter 12: Strawberries and Human Platelet Function
Abbreviations Used in This Chapter
12.1 Introduction
12.2 Polyphenols in Strawberries
12.3 Strawberry and its Cardio‐Protective Effects
12.4 Anti‐Platelet Factors in Strawberry
12.5 Discussion
References
Chapter 13: Effects of Metal Ions on Platelet Function
Abbreviations Used in This Chapter
13.1 Introduction
13.2 Zinc and Human Blood Platelet Function
13.3 Calcium and its Regulation of Platelet Function
13.4 Chromium and Platelet Function
13.5 Iron (Fe) and Platelet Function
13.6 Magnesium and Platelet Function
13.7 Platelet Function and Selenium
13.8 Conclusions
References
Chapter 14: Individual Compounds with Anti‐Platelet Activity Isolated from Plant Sources
Abbreviations Used in This Chapter
14.1 Introduction
14.2 Effects of Taurine and Glycine on Human Platelets
14.3 Anthocyanins and Human Platelets
14.4 Coumarins and Their Anti‐Platelet Effects
14.5 Atractylenolides and Their Anti‐Platelet Effects
14.6 Flavonolignans and Blood Platelet Function
14.7 Protocatechuic Acid on Human Platelet Aggregation
14.8 KOK and Platelet Function
14.9 Inhibitors of Platelet Granules Secretion
14.10 Hydroxychavicol and Platelet Function
14.11 Compounds Isolated from Guttiferae Species with Anti‐Platelet Activity
14.12 Conclusions

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