Our Wired Nerves The Human Nerve Connectome 1st Edition by Douglas Zochodne ISBN 0128214880 9780128214886
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ISBN 10: 0128214880
ISBN 13: 978-0128214886
Author: Douglas W. Zochodne
The nervous system is a complex, sophisticated system that regulates and coordinates body activities. It is made up of two major divisions: the central nervous system consisting of the brain and spinal cord and the peripheral nervous system. This consists of all other neural elements, including the peripheral nerves and the autonomic nerves. Peripheral nerves are the essential connections between the brain and spinal cord and the body. Without nerves there is no movement or sensation. Our Wired Nerves: The Human Nerve Connectome, reviews the essential anatomy and physiology of the peripheral nerve. It introduces the reader to what neuropathies are, how pain arises from damaged nerves and how nerves might be regenerated, including new and exciting ideas over how to coax their regrowth. Written by Dr. Douglas Zochodne leading expert in the field, and first book to focus on the Peripheral nerves it will surely be an essential reference for researchers and clinicians alike.
- Discusses the barriers to nerve regrowth and new strategies to reverse them
- Reviews of disorders of the peripheral nerves
- Exams reasons for nerve injuries
- Reviews recent discoveries in nerve research
Our Wired Nerves The Human Nerve Connectome 1st Table of contents:
Chapter 1: Elegant Wiring – Structural Beauty of the Peripheral Nervous System
- Nerve Structure and Organization
- Nodes of Excitability
- Nerve Terminals: Sockets and Interfaces
- Nerves for Muscle Movement
- Sensory Nerves and the Role of Infiltration
- Autonomic Axons: A Neglected System
Chapter 2: Constantly Thinking Physiology – Where Structure Meets Function
- The Function of Action Potentials
- Uncontrolled Action Potentials: Fasciculations, Pain, and Troubles
- Axoplasmic Transport: More Than Just Electrical Signals
- Reflexes and Nerve Activity
- Nerves and Muscles: Understanding Motor Units
- Walking and Movement: Nerves in Action
- Exquisite Sensation: Nerves in Sensory Perception
- Sensory Nerves: Not Just Bystanders
Chapter 3: Irreversible Events – Nerve Injury
- Types of Nerve Injuries
- Preferred Nerve Injuries: Which are Best for Recovery
- Permanent Nerve Damage and Recovery Challenges
Chapter 4: Testing the Peripheral Nervous System
- Neurological Examination: The Classic Approach
- Diagnostic Techniques: Shocks and Needles
- Imaging Nerves
- Nerve Biopsy for Diagnosis
- Blood Tests and Nerve Damage
Chapter 5: Understanding Neuropathies
- Mononeuropathies: Intense Pain and Disability
- Polyneuropathies: Common, Curious, and Various
- Diabetes and Nerve Damage
- Treating Diabetic Neuropathy in Rodents
- Inflammatory Polyneuropathies
- Leprosy
- Guillain-Barré Syndrome
- Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
- Critical Illness Polyneuropathy (Bolton’s Neuropathy)
- Inherited Polyneuropathies
Chapter 6: Locked In – Neurological Impairment
- Exploring the Locked-In Syndrome
Chapter 7: Disrupted Connectome and Pain
- How Nerve Connections Relate to Pain Perception
Chapter 8: Hope and Change – Nerve Regrowth
- The Remodeling of the Adult Nervous System
- Initial Clean-Up After Damage
- Growth Cones and Axon Guidance
- The Role of Snake Venom in Nerve Regeneration
- Inflammation’s Impact on Nerves
- Centralized Repair: Neuron HQ and Damaged Axons
- Can New Neurons be Created?
- Collateral Sprouting and Nerve Repair
- Developmental Molecules in Regeneration
- Summary of Nerve Regeneration Steps
Chapter 9: Clinics and Biology – Nerve Heroes and the Peripheral Nerve Society
- Focus on Key Figures and Organizations in Peripheral Nerve Research
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