Pharmaceutical Extrusion Technology, Second Edition Isaac Ghebre-Sellassie

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Product details:

• ISBN-10 ‏ : ‎ 0367735083
• ISBN-13 ‏ : ‎ 978-0367735081
• Author: Isaac Ghebre-Sellassie (Editor), Charles E. Martin (Editor), Feng Zhang (Editor), James DiNunzio (Editor)

The first edition of Pharmaceutical Extrusion Technology, published in 2003, was deemed the seminal book on pharmaceutical extrusion. Now it is expanded and improved, just like the usage of extrusion has expanded, improved and evolved into an accepted manufacturing technology to continuously mix active pharmaceutical ingredients with excipients for a myriad of traditional and novel dosage forms.
Pharmaceutical Extrusion Technology, Second Edition reflects how this has spawned numerous research activities, in addition to hardware and process advancements. It offers new authors, expanded chapters and contains all the extrusion related technical information necessary for the development, manufacturing, and marketing of pharmaceutical dosage forms.

Table of contents:

Chapter 1: Twin-Screw Extruders for Pharmaceutical Products from a Technical and Historical Perspective

Chapter 2: Extruder Design

Chapter 3: Control Strategy Considerations for Continuous Manufacturing Using Hot Melt Extrusion

Chapter 4: Twin-Screw Extrusion and Screw Design

Chapter 5: Die Design

Chapter 6: Feeding Technology and Material Handling for Pharmaceutical Extrusion

Chapter 7: Rheology, Torque, and Oscillatory Rheometers

Chapter 8: Foam Extrusion

Chapter 9: Melt Pelletization and Size Reduction: Powder to Pellets and Powder to Powder

Chapter 10: Extended-Release Dosage Forms Prepared Using Twin-Screw Extrusion

Chapter 11: Shape Extrusion—Extruded Implantable Drug Delivery Devices: Materials, Applications, and Processing

Chapter 12: Film, Sheet, and Laminates

Chapter 13: Melt Extruded Amorphous Solid Dispersions

Chapter 14: Process Modeling and Simulation of Extrusion Operations

Chapter 15: Devolatilization via Twin-Screw Extrusion: Theory, Tips, and Test Results

Chapter 16: Continuous Oral Solid Dose Manufacture

Chapter 17: Installation, Commissioning, and Qualification

Chapter 18: Extrusion Control Systems

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