Systems Neuroscience in Depression 1st Edition by Thomas Frodl ISBN 0128024569 978-0128024560

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Product details: 

ISBN 10: 0128024569

ISBN 13: 978-0128024560

Author: Thomas Frodl
Systems Neuroscience in Depression provides a comprehensive overview of the normal and depressed brain processes as studied from a systems neuroscience perspective. Systems neuroscience uses a wide variety of approaches to study how networks of neurons form the bases of higher brain function. A broad overview is discussed starting with a background from neurodevelopment and neural understanding as well as novel treatment approaches for depression. This book covers basic developmental aspects and depressive psychopathology, as well as the basic scientific background from animal models and experimental research. Current advances in systems neuroscience are highlighted in studies from child and adolescent psychiatry. Integrated approaches are presented with regards to genetics, neuroimaging and neuroinflammation as well as neuroendocrinology. The field of systems and network neuroscience is evolving rapidly and this book provides a greatly needed resource for researchers and practitioners in systems neuroscience and psychiatry.

Table of contents:

Contributors

The Systems Neuroscience Approach

Part I. Developmental Aspects

Chapter 1. A Multilevel Developmental Psychopathology Systems Perspective on Depression

Chapter 2. Early Life Adversity and Risk for Depression: Alterations in Cortisol and Brain Structure and Function as Mediating Mechanisms

Part II. Experimental Systems Neuroscience

Chapter 3. Novel Targets in the Glutamate and Nitric Oxide Neurotransmitter Systems for the Treatment of Depression

Chapter 4. Anti-Inflammatory and Immune-Modulatory Therapeutic Approaches in Major Depression

Chapter 5. Molecular Mechanisms of Depression

Part III. Systems Neuroscience

Chapter 6. Epigenetic Mechanisms in Depression

Chapter 7. Identifying Large-Scale Neural Networks Using fMRI

Chapter 8. Imaging Functional Systems in Depression

Chapter 9. Integrating the Stress Systems and Neuroimaging in Depression

Chapter 10. Depression in Children and Adolescents

Chapter 11. Systems Neuroscience in Late-Life Depression

Chapter 12. Arousal Regulation in Affective Disorders

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Tags: Thomas Frodl, Systems Neuroscience, Depression