Textbook of Drug Design and Discovery 5th Edition by Kristian Stromgaard, Povl Krogsgaard-Larsen, Ulf Madsen – Ebook PDF Instant Download/Delivery: 1498702783, 978-1498702782
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Product details:
ISBN 10: 1498702783
ISBN 13: 978-1498702782
Author: Kristian Stromgaard, Povl Krogsgaard-Larsen, Ulf Madsen
Building on the success of the previous editions, the Textbook of Drug Design and Discovery, Fifth Edition, has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine. The information is presented in an up-to-date review form with an underlying and fundamental focus on the educational aspects.
Beginning with an introduction to drug design and discovery, the first eight chapters cover molecular recognition, ligand-based drug design, and biostructure-based drug design. The authors also discuss drug-like properties and decision making in medicinal chemistry, chemical biology, natural products in drug discovery, and in vivo imaging in drug discovery.
The middle six chapters provide an overview of peptide and protein drug design, prodrugs in drug design and development, and enzyme inhibitors. The authors also go through receptors (structure, function, and pharmacology), ion channels (structure and function), and neurotransmitter transporters (structure, function, and drug binding).
The following chapters address important neurotransmitter systems, GABA and glutamic acid receptors and transporter ligands, acetylcholine, histamine, dopamine and serotonin, and opioid and cannabinoid receptors. The book concludes with an examination of neglected diseases, anticancer agents, tyrosine kinase receptors, and antibiotics.
Textbook of Drug Design and Discovery 5th Table of contents:
Chapter 1 Introduction to Drug Design and Discovery
Chapter 2 Molecular Recognition
Chapter 3 Ligand-Based Drug Design
Chapter 4 Biostructure-Based Drug Design
Chapter 5 Drug-Like Properties and Decision Making in Medicinal Chemistry
Chapter 6 Chemical Biology
Chapter 7 Natural Products in Drug Discovery
Chapter 8 In Vivo Imaging in Drug Discovery
Chapter 9 Peptide and Protein Drug Design
Chapter 10 Prodrugs in Drug Design and Development
Chapter 11 Enzyme Inhibitors: Biostructure- and Mechanism-Based Design
Chapter 12 Receptors: Structure, Function, and Pharmacology
Chapter 13 Ion Channels: Structure and Function
Chapter 14 Neurotransmitter Transporters: Structure, Function, and Drug Binding
Chapter 15 GABA and Glutamic Acid Receptor and Transporter Ligands
Chapter 16 Acetylcholine
Chapter 17 Histamine Receptors
Chapter 18 Dopamine and Serotonin
Chapter 19 Opioid and Cannabinoid Receptors
Chapter 20 Neglected Diseases
Chapter 21 Anticancer Agents
Chapter 22 Targeting Receptor Tyrosine Kinases
Chapter 23 Antibiotics
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Kristian Stromgaard,Povl Krogsgaard Larsen,Ulf Madsen,Textbook,Drug,Design,Discovery 5th