The chemistry of contrast agents in medical magnetic resonance imaging 2nd Edition by Andre S Merbach, Lothar Helm, Éva Tóth ISBN 9781119991762 1119991765

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Product details:

ISBN 10:   1119991765

ISBN 13: 9781119991762

Author:  Andre S. Merbach, Lothar Helm, Éva Tóth

Magnetic Resonance Imaging (MRI) is one of the most important tools in clinical diagnostics and biomedical research. The number of MRI scanners operating around the world is estimated to be approximately 20,000, and the development of contrast agents, currently used in about a third of the 50 million clinical MRI examinations performed every year, has largely contributed to this significant achievement.

This completely revised and extended second edition: 

• Includes new chapters on targeted, responsive, PARACEST and nanoparticle MRI contrast agents.
• Covers the basic chemistries, MR physics and the most important techniques used by chemists in the characterization of MRI agents from every angle from synthesis to safety considerations.
• Is written for all of those involved in the development and application of contrast agents in MRI.
• Presented in colour, it provides readers with true representation and easy interpretation of the images. 

Table of contents: 

1. General Principles of MRI

2. Relaxivity of Gadolinium(III) Complexes: Theory and Mechanism

3. Synthesis and Characterization of Ligands and their Gadolinium(III) Complexes

4. Stability and Toxicity of Contrast Agents

5. Structure, Dynamics, and Computational Studies of Lanthanide-Based Contrast Agents

6. Electronic Spin Relaxation and Outer-Sphere Dynamics of Gadolinium-Based Contrast Agents

7. Targeted MRI Contrast Agents

8. Responsive Probes

9. Paramagnetic CEST MRI Contrast Agents

10. Superparamagnetic Iron Oxide Nanoparticles for MRI

11. Gd-Containing Nanoparticles as MRI Contrast Agents

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Tags: Andre S Merbach, Lothar Helm, Éva Tóth, Chemistry, Contrast Agents, Medical Magnetic, Resonance Imaging