The Cutaneous Lymphoid Proliferations A Comprehensive Textbook of Lymphocytic Infiltrates of the Skin 2nd Edition by Cynthia Magro, Neil Crowson, Martin Mihm ISBN 1118776445 9781118776445

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ISBN 10:      1118776445
ISBN 13: 978-1118776445
Author:      Cynthia M. Magro, A. Neil Crowson, Martin C. Mihm Jr

The Cutaneous Lymphoid Proliferations A Comprehensive Textbook of Lymphocytic Infiltrates of the Skin 2nd Table of contents:

CHAPTER 1: Introduction to the Classification of Lymphoma

• Kiel Lukes–Collins Working Formulation classifications
• WHO, REAL, EORTC, and the Combined WHO/EORTC classifications
• Summary
• References
• Appendix: Definitions of Key Terms and Techniques
  • Plasma Cell Markers
  • Natural Killer Cell-Associated Markers
  • Cytotoxic Protein Markers
  • B Cell Markers
  • Myelomonocytic Markers, Including Dendritic Cell Markers
  • Follicular Dendritic Cell Markers
  • Special Techniques
  • Summary of Antibodies, Clones, and Dilutions

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CHAPTER 2: The Therapy of Cutaneous T Cell Lymphoma

• Introduction
• Diagnostic Work-Up and Staging Procedures
• CTCL Therapies:
  • Goals of Therapy in Advanced-Stage CTCL
  • Extracorporeal Photopheresis (ECP)
  • Interferons
  • Retinoids
  • Immunotoxins
  • Monoclonal Antibodies
  • Histone Deacetylase Inhibitors (HDACi)
  • Antibody-Drug Conjugates (ADC)
  • Cytotoxic Chemotherapy
  • Investigational Therapies (TLR Agonists and Cytokines)
  • Allogeneic Hematopoietic Stem Cell Transplantation (allo-HSCT)
• References

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CHAPTER 3: Molecular Analysis in Cutaneous Lymphoid Proliferation

• Introduction
• Immunoglobulin and T Cell Receptor Structure
• PCR Design for Determination of Clonality
• Detection of PCR Products for Clonality
• Evaluation of Results
• The Value and Utility of Molecular Diagnostics in Primary Cutaneous Lymphomas
• Limitations of Clonality Assessment by PCR
• Case Vignettes
• References

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CHAPTER 4: Benign Lymphocytic Infiltrates

• Introduction
• Spongiotic and Eczematous Dermatitis
• Other Spongiotic/Eczematous Tissue Reactions
• Causes of Subacute Eczematous Dermatitis
• Interface Dermatitis: Cell-Poor Vacuolar Interface Dermatitis
• Interface Dermatitis: Lichenoid Pattern
• Diffuse and Nodular Lymphocytic Dermal Infiltrates Without Atypia
• Diffuse and Nodular Lymphocytic Infiltrates Associated with Autoimmune Disease
• References

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CHAPTER 5: Reactive Lymphomatoid Tissue Reactions Mimicking Cutaneous T and B Cell Lymphoma

• Lymphomatoid Drug Eruptions
  • Molecular Profile of Lymphomatoid Drug Eruptions
  • Pathogenetic Basis of Lymphomatoid Drug Reactions
• Reactive Lymphomatoid Lesions in Collagen Vascular Disease
• Angiomatous Variants of Pseudolymphoma
• Case Vignettes
• References

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CHAPTER 6: Precursor Lesions of Cutaneous T Cell Lymphoma

• Cutaneous T Cell Lymphoid Dyscrasia
• Large Plaque Parapsoriasis
• Hypopigmented Interface T Cell Dyscrasia
• Pigmented Purpuric Dermatosis (PPD)
• Pityriasis Lichenoides
• Idiopathic Erythroderma (Pre-Sézary Syndrome)
• Syringolymphoid Hyperplasia with Alopecia
• Folliculotropic T Cell Lymphocytosis/Pilotropic T Cell Dyscrasia
• Idiopathic Follicular Mucinosis/Alopecia Mucinosa
• Keratoderma-like T Cell Dyscrasia
• Atypical Lymphocytic Lobular Panniculitis
• Case Vignettes
• References

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CHAPTER 7: Marginal Zone Lymphoma and Other Related Post Germinal Center B Cell Lymphoproliferative Disorders of The Skin

• Marginal Zone Lymphoma
• Blastic Marginal Zone Lymphoma
• Epidermotropic Marginal Zone Lymphoma
• Castleman Disease
• Primary Cutaneous Plasmacytoma
• Primary Cutaneous Light Chain Associated Cutaneous Amyloidosis
• Case Vignettes
• References

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CHAPTER 8: Primary Cutaneous Follicle Center Cell Lymphoma

• Clinical Features
• Pathology
• Phenotypic Profile
• Molecular Studies
• Pathogenesis
• Cytogenetics
• Case Vignettes
• Additional Molecular and Cytogenetic Study
• References

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CHAPTER 9: Primary Cutaneous Diffuse Large B Cell Lymphoma Including the Leg Type and Precursor B Cell Lymphoblastic Lymphoma

• Primary Cutaneous Diffuse Large B Cell Lymphoma
• Systemic Diffuse Large B Cell Lymphomas with Propensity to Involve the Skin
• Case Vignettes
• Additional Light Microscopic, Phenotypic, Molecular, Cytogenetic Studies
• References

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CHAPTER 10: Intravascular Lymphoma

• Clinical Features
• Light Microscopic Findings
• Phenotypic Profile
• Molecular and Cytogenetic Studies
• Pathogenesis
• Differential Diagnosis
  • Intravascular Anaplastic Large Cell Lymphoma
  • Benign Intravascular Proliferations of Histiocytes and Reactive T Cells
• Case Vignettes
• References

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CHAPTER 11: Cutaneous Mantle Cell Lymphoma

• Clinical Features
• Light Microscopic Findings
• Phenotypic Profile
• Molecular Studies
• Cytogenetic Profile
• Pathogenesis
• Case Vignettes
• Additional Molecular and Cytogenetic Studies
• References

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CHAPTER 12: Mycosis Fungoides and Sézary Syndrome

• Definition
• Mycosis Fungoides
• Sézary Syndrome and Erythrodermic Mycosis Fungoides
• Large Cell Transformation of Mycosis Fungoides
• Extracutaneous Involvement in Mycosis Fungoides
• Case Vignettes
• References

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CHAPTER 13: CD30-Positive Lymphoproliferative Disorders

• Lymphomatoid Papulosis
• Borderline CD30-Positive Lymphoproliferative Disorders
• Cutaneous Anaplastic Large Cell Lymphoma
• Small Cell ALCL
• Breast-Implant-Associated ALCL
• Intravascular ALCL
• Sarcomatoid ALCL
• CD30-Positive Large B Cell Lymphoma
• Case Vignettes
• References

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CHAPTER 14: CD4+ Peripheral T Cell Lymphoma, NOS, Including Primary Cutaneous CD4+ Small/Medium-Sized Pleomorphic T Cell Lymphoma

• Introduction
• Primary Cutaneous CD4+ Small/Medium-Sized Pleomorphic T Cell Lymphoma
• CD30-Negative Large Cell T Cell Lymphoma
• Cutaneous Follicular Helper T Cell Lymphoma
• Prognosis of Primary Cutaneous Peripheral T Cell Lymphoma, Unspecified
• Case Vignettes
• References

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CHAPTER 15: Subcutaneous Panniculitis-Like T Cell Lymphoma

• Clinical Features
• Morphology
• Phenotype
• Molecular Studies
• Differential Diagnosis
• Case Vignettes
• References

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CHAPTER 16: CD8 T Cell Lymphoproliferative Disease of the Skin

• Overview
• Classification of Primary CD8+ Cutaneous T Cell Lymphomas
• Histomorphology of Primary Cutaneous CD8+ T Cell Lymphoma
• Case Vignettes
• References

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CHAPTER 17: Nasal and Related Extranodal NK/T Cell Lymphomas and Blastic Plasmacytoid Dendritic Cell Neoplasm

• Biology of NK and NK-Like T Cells
• NK/T Cell Lymphoma
• Nasal NK/T Cell Lymphoma
• Case Vignettes
• References

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CHAPTER 18: Primary Cutaneous γδ T Cell Lymphoma

• Introduction
• Case Vignettes
• Additional Supplemental Figures
• References

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CHAPTER 19: Epstein–Barr Virus-Associated Lymphoproliferative Disease

• Introduction
• Hydroa Vacciniforme-Like EBV-Associated T Cell Lymphoproliferative Disease
• EBV+ Cutaneous B Cell Lymphoproliferative Disorder of the Elderly
• EBV-Associated Mucocutaneous Ulcer
• General Principles of EBV-Associated Lymphomagenesis
• Case Vignettes
• References

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CHAPTER 20: Hodgkin Lymphoma of the Skin

• Clinical Features
• Subtypes of Hodgkin Lymphoma
• Case Vignettes
• References

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CHAPTER 21: Chronic Lymphocytic Leukemia of B Cell and T Cell Prolymphocytic Leukemia

• B Cell Chronic Lymphocytic Leukemia
• T Cell Prolymphocytic Leukemia
• Case Vignettes
• References

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CHAPTER 22: Adult T Cell Leukemia/Lymphoma

• Clinical Features
• Pathology
• Phenotypic Studies
• Pathogenesis
• Infective Dermatitis of Childhood
• Case Vignettes
• References

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CHAPTER 23: Angioimmunoblastic Lymphadenopathy/Angioimmunoblastic T Cell Lymphoma

• Clinical Features
• Light Microscopic Findings
• Phenotypic Studies
• Molecular Studies
• Pathogenesis
• Case Vignettes
• References

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CHAPTER 24: Lymphomatoid Granulomatosis

• Introduction
• Clinical Features
• Histopathology
• Histogenesis
• Clonality Studies
• Differential Diagnosis
• Case Vignettes
• References

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CHAPTER 25: Cutaneous Infiltrates of Myeloid Derivation

• Introduction
• Leukemia Cutis
• Clonal Histiocytopathy Syndromes
• Histiocytopathy of Factor XIIIA Perivascular Dermal Dendritic Cell Origin
• Case Vignettes

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