Therapeutic Applications of Adenoviruses 1st Edition by Philip Ng, Nicola Brunetti Pierri ISBN 1498745482 9781498745482

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ISBN 10: 1498745482 
ISBN 13: 9781498745482
Author: Philip Ng, Nicola Brunetti-Pierri

Adenoviruses are double stranded DNA viruses that have been used to study the process of DNA replication. Studies of the mode of action of adenovirally produced tumors in rodents led to the discovery of tumour supressor genes. The adenoviral vector is now the most used vector in clinical gene therapy especially for some kinds of cancers. The chapters in this book focus on the most up-to-date developments in the therapeutic applications of adenoviruses. The intended audience is individuals in the Life Sciences interested in therapeutic applications of adenoviruses. This book reviews the life history and immune responses to adenoviruses and summarizes various therapies implemented with the use of adenoviruses.

Therapeutic Applications of Adenoviruses 1st Table of contents:

Chapter 1 Adenovirus Biology and Development as a Gene Delivery Vector
Chapter 2 Innate and Adaptive Immune Responses to Adenovirus
Chapter 3 Helper-Dependent Adenoviral Vectors for Cell and Gene Therapy
Chapter 4 Chemical and Combined Genetic and Chemical Modifications of Adenovirus Vector Capsids to Overcome Barriers for In Vivo Vector Delivery
Chapter 5 Design and Applications of Adenovirus-Based Hybrid Vectors
Chapter 6 Adenovirus Vectors for Genome Editing Involving Engineered Endonucleases
Chapter 7 Adenoviruses for Vaccination
Chapter 8 Use of Oncolytic Adenoviruses for Cancer Therapy

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Philip Ng,Nicola Brunetti Pierri,Therapeutic Applications,Adenoviruses