Topology and Physics of Circular DNA First Edition by Alexander Vologodskii ISBN 1315121301 9781315121307
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Product details:
ISBN 10: 1315121301
ISBN 13: 9781315121307
Author: Alexander Vologodskii
Topology and Physics of Circular DNA presents comprehensive coverage of the physical properties of circular DNA. The author examines how topological constraints arising from cyclization of DNA lead to distinctive properties that make closed molecules radically different from linear DNA. The phenomenon of supercoiling, its geometric and topological analysis, and the formation of noncanonical structures in circular DNA under the influence of supercoiling are emphasized. The combination of consistent theoretical analysis and detailed treatment of major experimental approaches make Topology and Physics of Circular DNA an important reference volume for biophysicists, biochemists, molecular biologists, and researchers and students who want to expand their understanding of circular DNA.
Table of contents:
Chapter 1 – Basic Physical Properties of DNA
Chapter 2 – Circular DNA and Supercoiling
Chapter 3 – Geometry and Topology of Circular DNA
Chapter 4 – Formation of Noncanonical Structures Under the Impact of Negative Supercoiling
Chapter 5 – The Use of Circular DNA in Studies of the Double Helix and its General Properties
Chapter 6 – DNA Supercoiling Inside the Cell
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Tags: Alexander Vologodskii, Topology and, Physics of Circular DNA
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