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Product details:
- ISBN-10 : 0127999612
- ISBN-13 : 978-0127999616
- Author: Annabelle Rodriguez-Oquendo
Translational Cardiometabolic Genomic Medicine,edited by Dr. Annabelle Rodriguez-Oquendo, is an important resource to postgraduate (medical, dental and graduate) students, postdoctoral fellows, basic scientists, and physician scientists seeking to understand and expand their knowledge base in the field of genomic medicine as it is applied to cardiometabolic diseases.
This handbook integrates cutting-edge experimental approaches such as chromatin immunoprecipitation paired end tagging (CHIA-PET), to population studies such as the Multi-Ethnic Study of Atherosclerosis.
It encompasses a range of book chapters that highlight bioinformatic approaches to better understanding functionality of the noncoding regions of the human genome to the use of molecular diagnostic testing in predicting increased risk of cardiovascular diseases. Where applicable, this reference also includes chapters related to therapeutic options specifically aligned to molecular targets.
- Provides comprehensive research on translational genomic medicine
- Explains state-of-the-art genome editing for stem cells and mouse models with significant relevance to human cardiometabolic disease
- Includes discussions on the functional effects of single nucleotide polymorphisms and cardiometabolic diseases, stratified by sex and race
- Encompasses a range of book chapters that highlight bioinformatic approaches to better understanding functionality of the noncoding regions of the human genome
Table of contents:
Chapter 1. Metabolomics and Cardiovascular Medicine
Chapter 2. Modern Transcriptomics and Small RNA Diversity
Chapter 3. A Systems-Level Understanding of Cardiovascular Disease through Networks
Chapter 4. Using Information about DNA Structure and Dynamics from Experiment and Simulation to Give Insight into Genome-Wide Association Studies
Chapter 5. Genomic Medicine and Lipid Metabolism: LDL Targets and Stem Cell Research Approaches
Chapter 6. Discovery of High-Density Lipoprotein Gene Targets from Classical Genetics to Genome-Wide Association Studies
Chapter 7. The Genetics of Obesity
Chapter 8. The Epidemiology and Genetics of Vascular Dementia: Current Knowledge and Next Steps
Chapter 9. Genomic Medicine and Ethnic Differences in Cardiovascular Disease Risk
Chapter 10. Genomics-Guided Immunotherapy of Human Epithelial Ovarian Cancer
Chapter 11. Overview of the Intersection of Genomics of Cholesterol Metabolism and Cardiometabolic Disease with Reproductive Health, Especially in Women
Chapter 12. Overview of Intersection of Genomics of Cardiometabolic Disease and Other Disease States, Such as Eye Health (Macular Degeneration)
Chapter 13. Translating Genomic Research to the Marketplace
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